It is not possible, in any way, to refer to the binomial health and well-being, without first characterizing these two words. Health is not-in any way-the absence of somatic or psychic illness, but rather the bio-psycho-socio-cultural and spiritual balance in which the self-rests, the authentic, the true, while well-being is conceptualized by the science of Martí of the spirit as the state of mind of the human being, whose physical, mental and spiritual conditions provide a feeling of satisfaction and tranquility

Introduction: A hemorrhagic stroke results in a sudden neurological deficit secondary to an eruption of blood in the cerebral parenchyma. External CSF drainage is indicated in cases of intracranial hypertension following acute hydrocephalus due to ventricular flooding. Objective: Evoke the postoperative prognosis of hemorrhagic stroke treated by external ventricular bypass in the context of Madagascar Materials and Methods: We conducted a descriptive retrospective study of 61 cases of hemorrhagic stroke treated by external ventricular drainage at the Neurosurgery and Surgical Resuscitation Department of the CHUJRA, between January 2018 and December 2020. The epidemio-clinical, computed tomographic, therapeutic and outcome parameters are described in order to identify the postoperative prognosis using the preoperative ICH score.

In the 21st century, the world is experiencing unwanted cata- strophic issues that are affecting billions daily, including climate change, politically based hate, war, gun violence, anti-women’s rights, COVID, an out-of-control drug epidemic, and a global mental health crisis [1]. Since 2015, the United Nations Office on Drugs and Crime (UNODC), World Health Organization (WHO), and Informal Scientific Network (ISN) have strived to bring the voice of science, as it pertains to addiction medicine, to inform critical discussions at the Commission on Narcotic Drugs (CND), the policymaking body of the United Nations with prime responsibility for drug control matters [2]. The opioid overdose crisis represents an increasingly global challenge, one associated with high rates of morbidity and mortality [3]. The contours of the epidemic have been most extensively documented in North America, but serious situations are developing around the world. Meanwhile, millions of people worldwide suffer from moderate to severe pain without access to opioid analgesics, despite the provisions of the international drug conventions. For these reasons, during the CND’s 61st session, the ISN examined the opioid overdose crisis and presented a statement with recommendations for consideration by the CND

Introduction: Multiple sclerosis is one of the common disabling neurological disorders. Cognitive deficits are emerging as the main cause of change in professional and social life. The P-300 event related potentials are delayed in latency in various disorders characterised by dementia. Here, we study the correlation of the event related potentials with cognitive decline in MS patients. Aims and Objectives: To evaluate patients with multiple sclerosis clinically and electro physiologically measuring event related potentials in respect of latency and amplitude and to co-relate it with cognitive decline

oods not only supply energy but also help in growth, development and maintenance of health including cognitive functions. It has also been observed that specific nutrients can affect cognitive abilities at different ages. Diverse nutrients present in the food play a crucial role in the maintenance of cognitive functions and deficiencies of such nutrients might lead to neurodegenerative diseases such as Alzheimer disease, Parkinson’s disease and other neuronal dysfunction including dementia. The purpose of the present study is to determine the existing data available in different science literature regarding food items available in India that have potent action on brain function. S

Background: Discoveries in this study can significantly improve the health and quality of life of over ten million Parkinson’s- affected people. Clinicians prescribe AntiParkinsonian medications to treat Parkinson’s illnesses and Parkinsonism. AntiParkinsonian Carbidopa-Levodopa, Ropinirole, and Pramipexole commonly cause progressive neural damage (augmentation) and adverse reactions such as excessive sedation, sudden passing out, and slowed cognition. This study presents a neurobiochemistry analysis regarding the world’s first long-term treatment of Parkinson’s with Methylphenidate. The neurobiochemistry analysis in this study describes and explains how Methylphenidate adjunctive therapy counteracts the adverse effects of AntiParkinsonians and how Methylpheni date monotherapy controls motor and non-motor symptoms, strengthens neural tissues, sustains alertness and cognition, and slows progressive worsening

This manuscript will review the crucial role of BDNF as a pain mediator and modulator of neuroinflammation and neuropathic pain. BDNF belongs to of the neurotrophin family of growth factors that is encoded by the bdnf gene. Its role as modulator was found to act on neuronal excitability and synaptic plasticity has triggered huge interest in neurobiological pain research. This pointed to renewed interest as a potential target for pharmacological agents in its long cascade of mechanism of actions

Stroke as a rife neurological emergency of note across different age-related, gender-based, economic, and racial lines is now more with us than ever before. Cerebrovascular accident, as it is otherwise called, constitutes a major clinico-epidemiologic bur- den to conscientious neurological emergency physicians, neurologists and neurosurgeons both at the public and private emergency departments of tertiary health institutions, home and abroad, and in the public domains premised on the loads of stroke patients referred from neighboring peripheral facilities or presenting directly to the emergency departments.

Vascular calcification is an important characteristic of atherosclerosis. According to histological analyses, bone formation tends to occur in heavily calcified carotid lesions devoid of ulceration and hemorrhage. Vascular calcification is not a simple degenerative and necrotic process associated with atherosclerosis but an active process similar to bone for- mation. Proteins involved in regulating skeletal bone formation are present in human atherosclerotic lesions. These proteins include osteoprotegerin and its ligand, bone sialoprotein, bone morphogenetic protein (BMP)-2 and BMP-4, osteocalcin, osteonectin, matrix Gla protein, and osteopontin

Everyone experiences stress at some point in life: the death of a loved one, a job changes, and even any day-to-day responsibilitycan trigger stress. And while it is true that the results of many scientific-medical studies support short-term stress as a key element in survival, in the long term the consequences it implies for the body can be devastating.

This work identifies the use of social networks and interpersonal relationships in the teachers and students of an Institution of Higher Education. The research was carried out in the Academic Unit of Education of the Catholic University of Cuenca, to determine to what extent the social networks influence the interpersonal relations of students and teachers. This is quantitative research that is based on bibliographical and descriptive research.

The study was conducted on 784 students aged 14 to 17 (383 boys and 401 girls), who were randomly selected, in Son La prov- ince. Following the standards of morphological and anthropological studies, this study aims to investigate IQ and find out the corre- lation between IQ and the fingerprint patterns of these teenagers. The results show that the average IQ of 14-17-year-old students is 102.28 points, with an annual increase of about 2.01 per year.

In India, amisulpride comparatively new antipsychotic which is claimed to be effective in both positive and negative symptoms schizophrenia and other disorder even though it has little or no action on serotonergic receptors. Lower striatal dopaminergic re- ceptor binding capacity and limbic selectivity causes of EPS. But, in clinical practice, we are getting EPS with this drug even at lower doses. Reported two cases of akathisia, drug- induced Parkinsonism and one case of galactorrhea, amenorrhea.

It is suggested that suicide among healthcare professionals is under-reported. It is still unknown if the under-reporting is due to considerations and empathy of colleagues, “blind-spot” of co-workers or any other reasons. In any case elucidation should lead to preventative measures

Low-level laser (light) therapy, LLLT, is a therapeutic application of light delivered as photons. The ability of absorbed light able to induce physiological effects is known as photobiomodulation. LLLT photobiomodulation is well-documented to provide clinical ben- efits of improved rates of healing attributed to anti-inflammatory effects, decreased pain, and enhanced tissue regeneration. These clinical outcomes correlate to the mechanism of action of LLLT’s photobiomodulation effects of increased generation of ATP and the ability to modulate inflammatory signaling molecules known to influence rapid and optimal tissue healing repair and regeneration. The clinical benefits of 635 nm LLLT is highlighted from a molecular mechanism of action perspective.

We have already known that child phycology is more times sensitive than other young adult. Concerning this issue, I want to explain one case study I did. It is a case of schoolgirl who suffered with child rapes in many times in tuition center, school, and even college while she was less than 18 years in age. The main cause was lack of love of parent and ignorance on child behaviors. She always expects a lot of love from her parent specially father, but her father had very rude behavior with her daughter while she was present in her home. Even she could not eat her breakfast with her father

Background: Trigeminal neuralgia (TN) caused solely by veins is relatively rare, and it is more difficult to visualize the responsible vein than the artery using MRI. There has been no comprehensive description of the condition and best practices for diagnosing and surgically treating it. Here, we aimed to visualize the vein causing TN and discuss intraoperative considerations in view of the report- ed relatively highly frequent recurrence of TN with vein compared to TN with arterial compression.

We have already known that child phycology is more times sensitive than other young adult. Concerning this issue, I want to explain one case study I did. It is a case of schoolgirl who suffered with child rapes in many times in tuition center, school, and even college while she was less than 18 years in age. The main cause was lack of love of parent and ignorance on child behaviors. She always expects a lot of love from her parent specially father, but her father had very rude behavior with her daughter while she was present in her home. Even she could not eat her breakfast with her father.

The definition of elderly can be described as: natural, progres- sive, spontaneous and irreversible physiological changes, in which both physical and mental strength are significantly impaired. Old age is conventionally synonymous with the onset of age 65

Pituitary adenomas are usually benign and present in two ways – either as an increase in the secretion of hormones or the tumor causing a mass effect on nearby structures. These presentations can include Acromegaly/gigantism, hyperprolactinemia, and Cushing’s syndrome. Transsphenoidal surgery is the first-line treatment for most pituitary adenomas and this study attempts to highlight the extent of functional remission in patients operated on at St John’s Hospital Bangalore for over one year