Cerebral palsy (CP) is a non-progressive brain disorder caused by immature brain development or injury. It results in motor impair- ment, often accompanied by sensory, perceptual, cognitive, communication, and behavioral disorders. This case report describes the treatment of a 2-year-old male patient diagnosed with cerebral palsy using Lius scalp acupuncture therapy, a method developed by Professor Liu Zhenhuan.

Central Auditory Processing Disorder [(C)APD] refers to difficulties in perceptual processing of information in the Central Auditory Nervous System (CANS) and underlying neurobiological mechanisms that supports a variety of auditory behaviours like temporal processing, auditory discrimination and binaural processing. CAPD may affect a person’s listening, communication abilities, academics etc thus it is paramount that individuals diagnosed with CAPD be provided significant management to conquer the deficit to the greatest degree possible. Speech and language pathologists provide several therapeutic strategies and approaches for the treatment of an individual with CAPD. The present article, therefore, reviews the therapeutic approaches offered by speech and language pathologists for the management of individuals with CAPD.

With the increase in life expectancy and the increase in health care services, the elderly population is increasing all over the world, so many countries are facing problems caused by the increase in the elderly population. On the other hand, due to the special conditions of the elderly and the multiplicity of ailments and lifestyle changes in families, some elderly people who get sick are entrusted to care centers and may move away from the path of a healthy and active old age. Among them, are elderly people who actively live with their families and realize the concept of active aging. In this manuscript, the researcher aims to examine the role of the family in active aging.

Neurocysticercosis (NCC) is a parasitic infection caused by the larval stage of Taenia solium, predominantly affecting the central nervous system. We present a case study of a 45-year-old gentleman who initially presented with migraine-like headaches and later developed vertigo, ultimately diagnosed with disseminated intracranial NCC. Despite an initial diagnosis of migraine and treatment with symptomatic medications, persistent symptoms prompted further investigation including a 3D MRI, revealing multiple cysticercal lesions throughout the brain parenchyma. The patient was subsequently treated with albendazole and corticosteroids, leading to resolution of symptoms but later experienced a seizure necessitating antiepileptic therapy.

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterised by upper and lower motor neuron dysfunction. Despite its devastating impact, and diagnostic challenges, a limited understanding of disease pathogenesis complicate effective management. Recent advancements in pharmacological therapies offer hope for improved outcomes. This review examines the current treatment landscape for ALS, including Riluzole (Rilutek, Tiglutik and Exservan), Edaravone (Radicava and Radicava ORS), and Tofersen (Qalsody), with a focus on their mechanisms, clinical efficacy, and implications for patient care.

Alzheimer’s disease (AD) is a complex and cognitive neurodegenerative disorder effecting millions of people across the globe. Emerging studies suggests that Triggering receptor expressed on myeloid cells 2 (TREM2) associated with late onset Alzheimer’s disease (LOAD). TREM2 are the trans membrane receptors of microglial cells which resides in central nervous system. TREM2 facilitates diverse physiological functions of microglia like phagocytosis. The signalling mechanism of TREM2 is still obscure, pertaining to the same we have proposed a hypothesis in our previous paper. In our hypothesis, we state that the ecto domain of TREM2 exhibit differential binding ability against various forms of Aß ligands. In the current work we have tested our hypothesis by utilising computational tools.