Cerebral venous sinus thrombosis (CVST) is a rare and potentially life-threatening condition that can result from various underlying etiologies, including metabolic disorders like homocystinuria and local infections such as mastoiditis. We report a case of an 8-year-old female with a background of homocystinuria who presented with CVST secondary to right-sided mastoiditis. On 2D echocardiography, she was found to have a clot in the left atrial appendage, along with concentric left ventricular hypertrophy.

Multimorbidity is common in stroke and contributes to poorer health status, high risk of mortality, and polypharmacy. Aim is to determine the prevalence of multimorbidity in stroke in India.

This comprehensive study addresses the critical need for evidence-based interventions and Driver Rehabilitation guidelines in Occupational Therapy (OT) programs aimed at post-stroke driver rehabilitation, specifically within the context of India. The research comprises two integral phases: a systematic review of relevant literature and the formulation of consensus guidelines.

Mental health and neurology have long been viewed as separate fields, but advances in research highlight the deep connections between them. As we better understand the brain, it’s clear that mental health conditions and neurological disorders often share overlapping biological and psychological pathways. Addressing these interconnections can lead to improved patient outcomes and more comprehensive approaches to treatment. To truly meet the needs of patients with conditions affecting the brain, we must close the gap between these two disciplines, fostering a more integrated and holistic healthcare approach.

Carbamazepine is usually the preferred first line of treatment for Trigeminal neuralgia, followed by some choice of drugs like Lamotrigine and Baclofen and anti-epileptics like Phenytoin, Gabapentin, Topiramate, Tocainide and Valproate. If there is a decrease in efficacy or development of tolerance to the drugs, some surgical modality needs to be considered. Factors such as pain relief, recurrence rate, morbidity, and mortality rates should be kept in mind while going through the treatment plan.

Goldberg-Shprintzen syndrome is a rare genetic Autosomal Recessive disorder, characterized by impaired intellectual development, dysmorphic facial features, and neurological anomalies. The KIFBP gene has been identified as the responsible gene for the syndrome. The KIFBP gene encodes a KIF-binding protein (KBP) which is expressed in the central and enteric nervous systems. KBP dysfunction affects neuronal migration, axonal extension, and neuronal apoptosis; therefore, it is thought to cause brain anomalies in patients with Goldberg-Shprintzen syndrome (GOSHS).

Acute flaccid myelitis is an asymmetric flaccid weakness of one or all four limbs preceded by a prodrome of fever with respiratory or gastrointestinal illness. Typically affecting healthy children, with a higher incidence in males, these cases often occur in clusters following Enterovirus outbreaks. While primarily documented in the United States, they have been reported worldwide. Acute flaccid myelitis has affected a vast majority of children leaving them with crippling disability.