Healthcare system is defined as activities whose primary purpose is to promote, restore or maintain life WHO (2000). It is delivered by medical and allied professionals to promote the quality of life among patients especially once diagnosed with terminal ailment. At the Perpetual Succour Hospital, Cebu City, Philippines a support group was created for Thyroid cancer survivor. However, one of the active members committed suicide later on his life. A peculiar case that was unlikely to all. According to studies, well differentiated thyroid cancer is responsive to Radioactive Iodine therapy and has good prognosis. However, people who survived the so called differentiated thyroid cancer who undergone RAI therapy still harbouring the thought of being inflicted with the big “C”. This cross-sectional study aimed to determine the quality of life of patients with well differentiated thyroid carcinoma undergoing Radioactive Iodine I-131 Therapy and their Suicidal Ideation at Perpetual Succour Hospital for the year 2018. This study proved that once the patient is diagnosed with cancer, changes in the age are associated with changes in the probability of the severity of the cancer by 1.12 times. The quality of life differs among statuses. The respondents who are married have better quality of life compared with the others, while separated ones have poorer life quality. Lastly, the study proved that the better the quality of life, the less likely for the patients to commit suicide hence, the patient who committed suicide was a separate case. This study could serve as a good mirror to people on different culture who are afflicted on the same ailment. But to those who are specifically identified to have poorer quality of life, special attention should be given by the clinicians.