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Articles of Volume : 2 Issue : 2, October, 2019 | |
| Attention Deficit Hyperactivity Disorder: definition, contexts, neural correlates and clinical strategies | Author : Giulio Perrotta | Abstract | Full Text | Abstract :Starting from the definition of "Attention Deficit and Hyperactivity Disorder" (ADHD), we proceeded to list the individual forms envisaged by the DSM-V, with a series of focus on clinical, neuropsychological and therapeutic profiles, concluding the analysis on the context resolution of the problems deriving from the disturbance in question. |
| | Specific Learning and Language Disorders: Definitions, Differences, Clinical Contexts and Therapeutic Approaches | Author : Giulio Perrotta | Abstract | Full Text | Abstract :In educational psychology, the specific disorders of learning and language probably represent the two most general categories among the subjects in the evolutionary phase under eighteen. Failure to diagnose leads to a high level of school exclusion and therefore, social marginalization, with an exponential danger of developing important latent psychopathologies. The present discussion first analyzes the definitions, differences and clinical contexts of reference, and then moves towards the best therapeutic approaches and techniques to help young patients to manage these disorders better. |
| | External evidence against using less-than complete abstinence as a primary outcome in addiction | Author : Thadakala Kiran | Abstract | Full Text | Abstract :“Addiction” is a complex neurobiological process of hedonic dysregulation. It is characterized in humans by compulsive use of substances, loss of control over the quantity consumed, and continued use despite the harm caused by the substance. Addicted individuals are prone to relapse that appears to be related to reexposure to the addicting substances, substance-related cues, and psychosocial stressors [1]. In this process, initial impulsivity is replaced by compulsivity [1]. The traditional method of treatment for addiction in the United States involves twenty-eight days of residential treatment. The follow-up recommendations by treatment centers generally amount to participation in twelve-step meetings. There is little financial incentive for rigorous follow-up in this model and the recovery rates following such treatments are unknown. Even if very generous definitions of success are applied, recovery rates remain low. However, for physicians, well-documented recovery rates following their initial residential treatment experience are high. Additionally, there is a movement in the field of addiction medicine to employ “Medication Assisted Treatment” (MAT). For example, its advocates recommend the use of medications such as naltrexone (Vivitrol®).The proponents of these medications, however, use curious outcome measures, rather than complete abstinence, to demonstrate their efficacy. This paper reviews and utilizes the neurobiology of addiction to compare and contrast the outcomes in different populations. It also reviews the outcome data on Vivitrol in particular. We believe that a clear understanding of the neurobiology of addiction is essential to understanding and correcting the vast outcome differences in various patient groups. |
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