Background: Its intriguing to learn about the various ways traditional plants can be used to treat medical issues. Many studies are being undertaken to see how traditional herbal fruits can help with a variety of medical conditions, including immunodeficiency syndrome. Methods: We employed network pharmacology to discover a biological link between the pharmacological effects of myrolan wood or Haritaki or Terminalia chebula, a traditional Asian medicinal fruit, and HIV pathogenesis in this study. Results: The scientists discovered the common pathway by blocking reverse transcriptase using interrelationship analysis. Conclusion: Terminalia chebula as an HIV treatment could be beneficial. More investigation into the usefulness of myrolan wood fruit in the treatment of HIV is recommended.

Nano-drugs have always been used as a new treatment for various cancers. Recently, many advances have been made in the use of nano-drugs, which has led to the introduction of nano-drugs as an important factor in the front line. Has been treated. Also, some of the nanoparticles studied have a dual use in the treatment and diagnosis of cancer cells, most research. Nano-drugs have been developed for breast and stomach cancers that have gone through their clinical phases, but in other cancers, most drugs are in phases 2 and 3; Unfortunately, there is no definitive cure for cancer, but recent advances in nanotechnology and nanomedicine, which have led to the development of new drugs, are helping to provide a better and less complication-free treatment for cancer. In this article, we provide an overview of the use of nanodrugs, their reported results, and their function as the mainstay of cancer treatment.

The target is to evaluate ascorbic acid effect on prevention or treatment of the most recent viral infection, SARS-CoV-2. Covid-19 is a Systemic disease that can cause a sharp increase in cytokines, resulting in pulmonary capillary endothelial cell activation. Increasing neutrophil infiltration and oxidative stress. Coronavirus activates macrophages to release molecules such as NO. Vitamin C enhance chemotaxism, migration and decreases ROS release. It also reduces the secretion of cytokines, especially 6-IL and TNF-a. Vitamin C can help increase the rate of recovery in hospitalization by 70% and quantitative analysis indicated that it may reduce patients symptoms by 30%. High dose Ascorbic acid infusion causes positive interference in sodium, glucose and creatinine also negative interference in lipase, Triglycerides, direct bilirubin and LDL / HDL cholesterol. Co-treatment of vitamin C with Melatonin, Vitamin D and Zinc can have a synergic effect on treatment. Although; in a study high doses of zinc gluconate and ascorbic acid, had no significant effect on reducing the course of symptoms.

Introduction: Biosafety constitutes a strategic approach to analyze, evaluate and manage, as well as to propose a system of actions to eradicate risks. Materials and methods: A prospective, analytical, observational study with a cross-sectional quantitative approach was carried out in three clinical laboratories of primary health care, selected by simple random sampling. The universe was made up of 37 workers, with inclusion criteria that were to be a laboratory worker and who had agreed to participate in the study and the exclusion criteria to be a student in training. The information collection instrument was the questionnaire, which contains 6 elements to evaluate related to biosafety training. The variables considered, age, sex, years of work. The variables were worked with an analytical evaluation in which percentages, mean, and Standard deviation were considered. Results: 45.9% of the workers had not received training in biosafety. The three polyclinics show a similar pattern of training (2 = 2.269, p = 0.322). After the training intervention received, 100% of the respondents evaluated it as sufficient and 89.1% above their expectations. Conclusions: Deficiencies in knowledge about biosafety were identified that were reversed with a training intervention that was considered sufficient by 100% of the respondents, therefore it is considered effective.

Acute coronary syndrome is the leading cause of mortality worldwide and prediabetes is among the leading risk factors. The study aimed to review the effects of prediabetes on acute coronary syndrome outcomes. A systematic literature search was conducted in the PubMed and Google Scholar for relevant articles published in English language during the period from 2009-August 2020. The keyword prediabetes, acute coronary syndrome, outcomes, revascularization, cardiovascular outcomes, and heart failure were used. Among the thirty-six articles retrieved, twenty-six full text were eligible. The authors name, country, year of publication, type of study and conclusion were recorded. Out of the manuscripts reviewed, seven were from Asia; seven were from Europe and the USA each, three from South America, and one from Australia. The studies were prospective cohort (13), 6 were cross-sectional, while seven were retrospective. The studies enrolled 360033 patients, the results were mixed with some studies showed the negative effects of PD on acute coronary syndrome outcomes, while other showed no effects. The studies showed conflicting effects regarding the effects of prediabetes on acute coronary syndrome outcomes.

The endocannabinoid system plays a physiological natural anti-infiammatory anticancer role and the pharmacological effects of cannabinoids from Cannabis plant simply reflect the action of the endogenous ones. Therefore, from a therapeutic point of view Cannabis plant cannot be understood without taking into consideration the physio-pathological role of the endocannabinoid system. Despite the great number of potentially therapeutic molecules with the Cannabis plant, they may be synthetized within four archetypic molecules, which consist of tetra-hydro-cannabinol (THC), cannabinol (CBN), cannabigerol (CBG) and cannabidiol (CBD). All molecules play a similar anticancer activity, whereas their psychological effects are different. THC is the only psychotropic psychedelic cannabinoid, whereas the other three cannabinoids have no psychotropic effect, but exert an important anxiolytic activity. Moreover, only THC acts as a direct enzyme responsible for cannabinoid degradation, by enhancing the endogenous cannabinoid content. Unfortunately, despite the great number of experimental studies, the clinical use of cannabinoids in the treatment of systemic human diseases is still at the beginning.