Hyaluronic acid fillers are one of the most frequently used in cosmetic procedures. They are popular because of their ability to restore volume to the face, which surgery isn’t capable of. Inside the skin, the implant is subjected to various mechanical forces that vary according to the anatomical area. Every filler has specific rheological properties which change the way it performs in the clinical environment. A sound understanding of how the anatomy of the face works, alongside the rheological properties of the filler, is vital for successful outcomes in facial rejuvenation procedures.

Background: Despite inroads in treatment and prevention, childhood febrile illnesses remain global public health issues. Optimal care-seeking by mothers could influence health outcomes. Objective: To assess the differences in care-seeking patterns and practices for childhood febrile illnesses among mothers of under– fives in urban and rural areas of Anambra state, Nigeria. Methods: This was a comparative cross-sectional analytical mixed-method study. Multistage sampling technique was used to enrol 600 mothers of under-five children accessing child welfare clinics at the Primary Health Care facilities in Anambra state. Analysis of data was carried out using SPSS version 22; with alpha set at p-value = 0.05.Triangulation of findings of the survey and thematic content analysis of the Focus Group Discussion was done. Results: Appropriate care was sought by 134 (44.7%) of the urban and 125 (43.2%) of the rural respondents (p = 0.458). Prompt appropriate care was sought by 122 (40.7%) of the urban and 98 (36.7%) of the rural respondents (p = 0.042). Distance to the health facility, determinant of place of care-seeking and possession of health insurance were significantly associated with appropriate and prompt care-seeking patterns among the mothers. Conclusions: Appropriate and prompt care-seeking is generally poor among the respondents in both localities. A reorientation of mothers on appropriate and prompt care-seeking practices through continuous health education and other awareness creation processes is needed

Introduction: PCOD (Polycystic Ovarian Disease) is a very disturbing condition of women of reproductive age, a common endocrine and metabolic disorder. Management of PCOD is a complex process, with inevitable long-term treatment, including appropriate medication and lifestyle changes. Yoga Prana Vidya (YPV) System protocols have been proven to have cured this condition, and this paper presents one such case healed successfully and holistically. The patient had symptoms of male pattern baldness, hair loss and Acne on face. Method: An in-depth case study method has been used in this paper, with data collection from patient records, YPV healer’s records and patient feedback. Results: The patient’s PCOD condition was cured completely after 1 month and 23 days of healing. Hair loss reduced significantly, and some hair re-growth was also achieved. Acne was cured later completely, after further 16 days of healing. The patient achieved greater emotional and mental stability, besides improving physically. The patient regained her self-confidence and self-esteem. Conclusions: PCOD is one of the most common endocrine disorders affecting females in their reproductive age, and may lead to serious complications, if due care and attention is not given. Yoga Prana Vidya (YPV) protocols are among proven methods of proper management of PCOD without use of any drugs. Further research using YPV with appropriate number of samples of cases like this case is recommended. It will be helpful for frontline health workers such as doctors and nurses to acquire a working knowledge of YPV practices and apply in practice to complement their specialties.

Background: Buruli ulcer is a chronic, debilitating, necrotizing disease of the skin and soft tissue caused by Mycobacterium ulcerans. Early detection and appropriate treatment of the patients are currently the most important measures for preventing the debilitating consequences of the disease. Objective: To assess the clinical profile of Buruli ulcer patients presenting in a referral hospital in Anambra state, Nigeria. Methods: A cross-sectional descriptive study was carried out among a cohort of 39 Buruli ulcer disease patients referred to a referral hospital in Anambra State between July and December 2021. A semi-structured, interviewer-administered questionnaire was used to collect data on the socio-demographic characteristics and the clinical presentation of the patients. Data were analyzed using SPSS version 22; with alpha set at p-value = 0.05. Results: Twenty one (53.8%) of the study participants were males while 18 (46.2%) were females. Their mean age was 28.41±18.668. Active lesions in the form of ulcers were seen in 38 (97.4%) of the participants while lesions were seen in the lower limbs in 35 (87.2%) of them. Statistically significant association existed between the clinical presentation of Buruli ulcer disease and the occupation of the respondents (p = 0.05). Conclusions: Buruli ulcer still exists in the Nigeria and presents majorly with ulcers on the lower limbs. Public health efforts aimed at patient education and to assist with early detection of the disease to minimize associated morbidity should be instituted.

The use of HAART for the treatment of HIV/AIDS infection, despite its success, has been reported to be accompanied by increased number of adverse drug reactions (ADRs) for which some risk factors such as age, gender, co-morbidities have been implicated. The association between alcohol consumption, herbal drug intake and use of co-trimoxazole and ADRs to HAART has not been documented much. The main objective of this study is to determine the association between alcohol consumption, herbal drug intake, use of co-trimoxazole and presentation of ADRs to HAART in HIV/AIDS patients in Makurdi where there’s high HIV infection, alcohol consumption and herbal use. It was a combination of prospective and retrospective study at FMC, Makurdi. We used clinical records of the patients and questionnaires for patients enrolled from January to October, 2019 and followed up for six months. The biodata, drug history including herbal medications and social life (use of alcohol) history were retrieved. A total number of three hundred and three (303) patients were recruited during the study period out of which two hundred and ten (210) patients were used. From a total of 210 patients, 144 (68. 6%) were females while sixty-six, 66 (31.4 %) were males. Of these, only 68(32.4%) patients took alcohol while 89 (42.4%) patients used herbal medications together with HAART regimen and 185(88.1) were on cotrimoxazole prophylaxis. 22 patients presented with ADR with peripheral neuropathy and insomnia being the commonest ADRs. 54.5% (majority) of the patients with ADRs took alcohol while 81.8% (majority) of the patients who developed ADRs were actually on herbal medications or co-trimoxazole. The p-value>0.05. Alcohol consumption, herbal medication use and co-trimoxazole prophylaxis in HIV/AIDS positive patients while on ARVs may increase ADRs to ARVs. Thus, HIV/AIDS patients should be discouraged from use of alcohol and herbal medication while on HAART.