Background: Hypertension is still a health problem in Indonesia, especially in Bandung. The increase in hypertension cases can be caused by unhealthy lifestyles. Purpose: This study aims to determine the effect of smoking and history of hypertension on the incidence of hypertension. Methods: This study used a cross-sectional design. The population of this study is a productive age community, which is between 15-60 years. The sample technique in this study used accidental sampling techniques and obtained samples of 67 people. The instrument used is a questionnaire. Data analysis using chi-square test. Results: More than half of respondents smoke (53.7%), most respondents have no family history of hypertension (55.2%), and more than half of respondents suffer from hypertension (52.2%). The variables that affect the incidence of hypertension are smoking (p = 0.005 and OR = 4.773 (1.696-13.427) and history of hypertension (p = 0.033 and OR = 2.933 (1.075-8.001). Conclusion: Smoking people are at risk of suffering from hypertension by 4.7 times greater than people who do not smoke and people who have a history of hypertension are at risk of suffering from hypertension by 2.9 times greater than people who have no family history of hypertension. Suggestion: It is recommended to people who smoke in order to stop smoking. Mainly are those who have a family history of hypertension.

Background: The elderly group tends to experience health problems caused by decreased body functions due to the aging process. So it is more susceptible to suffer from hypertension. Purpose: This study aims to determine the influence of characteristics on the incidence of hypertension in the elderly Method: The method used is quantitative with Cross Sectional design. The population of this study is a productive age community, which is between 15-60 years. The sample was taken in a simple random manner with a sample of 245 respondents. Data collection using questionnaires. The statistical test used is the chi square test Results: The results of this study showed a significant influence between the age of hypertension (p = 0.000). There is a significant influence between the history of hypertension and the incidence of hypertension (0.015). Gender was not a risk factor for hypertension (p = 1,000). Conclusion: The conclusion of this study is that people aged 60-74 are 4.2 times more likely to suffer from hypertension. People who have a history of hypertension are 1.9 times more likely to suffer from hypertension. While the sex variable could not be proven in this study. So it is necessary to educate people over 60 years old and have a history of hypertension to pay more attention to lifestyle and routinely check blood pressure.

The high maternal mortality rate (MMR) in Indonesia has made the government make efforts to reduce maternal mortality (MMR) as a priority program in health development. In general, there was a decrease in maternal mortality during the period 1991-2015 from 390 to 305 per 100,000 live births. The maternal and child health program is a priority of the Ministry of Health and the success of the Maternal and Child Health (MCH) program is a key indicator of the National Long-Term Development Plan (RPJPN) 2005-2025. This research is quantitative research in the nature of an analytical survey with a cross-sectional design. The population in this study is all pregnant women in Bandung City in 2022 as many as 398 pregnant women. The sampling technique uses purposive sampling which is a sampling technique based on “research” (judgment) Pregnant women who received satisfaction in access to antenatal care services amounted to 58.7% with a frequency distribution of 226 respondents. Meanwhile, pregnant women who lack access to antenatal care services amounted to 41.3 with a frequency distribution of 156.

Parenting applied by parents will affect the growth and development of toddlers because malnutrition during toddlerhood will be irreversible (cannot recover), so at this time, toddlers need quality food intake. The better the parenting style, the better the nutritional status. Good parenting is reflected in the better food intake given to toddlers. This type of research is descriptive qualitative analytics (exploratory study) using a cross-sectional design which is an analytical study to analyze the effect of fathers’ involvement in providing complementary foods with the incidence of stunting. The research was conducted in Bandung City, West Java Province. The population in this study was mothers who had toddlers aged 6-24 months. The sample in this study is fathers who have 102 toddlers living in Bandung City in 2022 using the proportional random sampling formula. In this study, the P-value was 0.291, which means there is no significant relationship between the involvement of fathers in providing complementary foods with the incidence of stunting in Bandung. Risk factors for stunting in toddlers are education level, local food processing, parental knowledge, health role power, and husband support. The factor most associated with stunting is paternal involvement.

Background : The outbreak of the new coronavirus, also known as COVID-19, began in Wuhan, China, in January 2020, becoming a sudden public health crisis and a severe threat to lives in most parts of the world. This study aimed to use a Geographic Information System (GIS) to study the spatial distribution of COVID-19 incidence in Ho Chi Minh city. Methods: the histogram was first used to study the distribution of the COVID-19 cases and COVID-19 incidence. A GIS was then employed to map the spatial distribution of the COVID-19 cases and COVID-19 incidence. Finally, the study results were discussed and concluded. Results: a large proportion of COVID-19 infections mainly appeared in districts in the eastern region, then followed by the western districts of the city, while the average rate of infections was concentrated in districts near the city center. Low rates of COVID-19 infection were detected in the northern and southern districts of the city and some central districts of the city. Conclusions: the study results indicated the effectiveness of a GIS for mapping COVID-19 incidence. Findings in this study provide an insight into the spatial distribution of infectious diseases and make great contributions to the control of the COVID-19 pandemic.

Quorum-sensing LasR antagonism is evolving as a primary focus in promising new antivirulence approaches for treating bacterial infections. Pseudomonas aeruginosa’s LasR is a target receptor for developing alternative medicines in chronic wounds because it acts as an autoinducer in biofilm formation. Our research aims to predict the biofunction of Psidium guajava leaf water extract as an inhibitor of the quorum-sensing LasR of Pseudomonas aeruginosa. The 3D structures of five bioactive compounds (quercetin, gallocatechin, esculin, 3-sinapoylquinic acid, ellagic acid) and N-3-Oxo-Dodecanoyl-L-Homoserine Lactone (as positive control) were obtained from the PubChem Database. The Protein Data Bank database is used to download LasR. The active site of the LasR protein was determined using Molegro Virtual Docker 5.0. The docking simulation uses Molegro Virtual Docker 5.0 and Discovery Studio program version 21.1.1 for visualization. The results showed that the five compounds could bind to LasR at the active site and substrate binding, leading to the compound’s potential as an antibacterial for Pseudomonas aeruginosa by inhibiting the quorum-sensing receptor LasR. The 3-sinapoylquinic acid-LasR complex shows the lowest binding energy, namely -311.2 kJ/mol.

Background: Earth observation data has established themselves as extremely useful and very diverse domains for research associated with space, spatio-temporal components, and geography. Following the outbreak of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) last December 2019 in China. This study aims to systematically review and synthetize perspectives from earth observation data to investigate the effects of COVID-19 on the environment. Material and Methods: A total of 41articles were first collected from four main digital databases including Web of Science, SCOPUS, PubMed/MEDLINE, and Google scholar. It will go on comprehensively review and synthesize applications of earth observation data in studies the COVID-19 impacts on environment. Specifically, the content is presented under three sub-sections; namely the use of earth observation data in (i) studies of impacts on water quality, (ii) studies of impacts on air quality, and (iii) studies of other impacts on the environment, respectively. Results: It was found that change in the intensity of air and water pollution after reduced anthropogenic activities around the world were captured by remote sensing – supplying concrete evidence that can help inform improved environmental policy during the COVID-19 pandemic. Conclusion: It can be concluded that the varied use of remote sensing techniques affirms the value of earth observation data to studies of infectious diseases to environment, especially in times of such large-scale disasters as the COVID-19 pandemic.