Introduction: in the General Teaching Hospital “Dr. Agostinho Neto”has not been characterized by spinal cord trauma. Objective: to characterize spinal cord trauma in the Neurosurgery Service of the General Teaching Hospital “Dr. Agostinho Neto”during the years 2013-2018. Method: a descriptive, retrospective and longitudinal study was carried out. The population consisted of 230 patients, from which a random sample was chosen (n=92). The following variables were studied: age, sex, time between trauma and specialized medical care, type of injury, causes of trauma. Results: the patients were mostly men (69.6%), were between 39 and 48 years (23.9%), vertebral fractures (59.8%), survived 95.7% and 56.5% were attended in the first 6 hours posttrauma. Conclusions: spinal cord traumas affect patients in the productive stage of life, which shows the social relevance of their study.

Introduction: oral cancer is a health problem that affects a significant group of people. Objective: to identify the clinical-epidemiological behavior of oral cancer in the province of Guantanamo in the 2007-2018 period. Method: a descriptive, cross-sectional study was carried out. The universe was the 252 patients with histopathological diagnosis of the disease. The following variables were studied: triennial involvement, age, sex, origin, oral topography, clinical extension and morphological type. Results: the highest percentage of the patients belonged to the male sex (69.4%), were over 60 years old (69.8%), came from the Guantánamo municipality (42.9%). The lesions were located mainly in the tongue (37.3%) and floor of the mouth (19.0%) and extended to the buccal complex (52.8%). Squamous cell carcinoma was the most common histopathological type (94%). Conclusions: in Guantanamo, oral cancer is an unsolved health problem that mainly affects the geriatric population and the male sex, which requires attention in advanced stages of the disease.

Introduction: the prescription of vitamin K inhibitor drugs requires control of the anticoagulant effect. Objective: to characterize patients with a history of treatment with warfarin sodium at the time of admission to the intensive care unit of the General Teaching Hospital “Dr. Agostinho Neto” during the 2016-2018 period. Method: an analytical, retrospective and longitudinal study was carried out. 54 patients with the characteristics indicated were studied, which were grouped in a control group (n=16) with adequate anticoagulation and a study group (n=38) also with adequate anticoagulation. Sociodemographic, clinical and laboratory variables were studied. Results: A total of 16 patients presented adequate level of anticoagulation and, in 38, level of anticoagulation was inadequate. Sodium warfarin was indicated more in patients with mechanical cardiac valve prostheses (20.0%), and inadequate anticoagulation was more common in these. The factors most related to adequate anticoagulation were frequent medical supervision (p=0.0000), who did not use drugs that interfere with the action of the drug (p=0.0000) and treatment compliance (p=0.0000). In 22 patients there were hemorrhagic complications and the most common was cerebral hemorrhage and, 16, they presented thromboembolic complications and the most frequent was cerebral embolism. Three patients died from bleeding complications and 9 from thromboembolic complications. In 21 patients the indication of the drug was inappropriate. Conclusions: the need to control the adequate therapeutic adherence of the patient is revealed because the inadequate anticoagulant effect generates complications that can determine the death of the patient.

Introduction: hyaline membrane disease is a health problem in the neonatal stage. Objective: to characterize the newborns admitted to the neonatal intensive care unit of the General Teaching Hospital “Dr. Agostinho Neto” due to hyaline membrane disease during the years 2016-2018. Method: an observational, descriptive, prospective and longitudinal study of 163 newborns who entered the unit was made. Results: 16.4% of the infants admitted to this unit had this disease and the lethality was 11.0%. The largest proportion of these were male (55.8%), were between 31.0 and 33.6 weeks of gestational age at birth (28.2%), weighed between 1500.9 and 1999.9 g (27.0 %), had an Apgar after 5 minutes of birth between 8 and 10 points (58.9%) and were in the unit for 7 to 14 days (40.4%). 93.3% were treated with pulmonary maturation inducing drugs and 100.0% with surfactant and conventional mechanical ventilation (100.0%). 84.7% presented complications and 55.6% died from intracranial hemorrhage (55.6%). It was common for mothers to be between 19 and 35 years old (76.6%), to be ceased (65.0%) and had pregnancy-related complications (82.2%). Conclusion: lethality was higher as the gestational age and birth weight decreased, in those who were not treated with pulmonary maturation inducing drugs and who presented meningoencephalitis.