Synthesis of some new pyridines, thienopyridines and pyridothienopyrimidines bearing 1,3-diphenyl-1H-pyrazole moiety | Author : Elham A. Al-Taifi,1Eman A. Thabet,2Etify A. Bakhite3* and Talaat I. El-Emary3 | Abstract | Full Text | Abstract :Abstract: 1-phenyl/(2-thienyl)-3-(1,3-Diphenyl-1H-pyrazol-4-yl)-2-propen-1-ones (3a,b) were prepared. Reaction of 3b with hydroxyl amine, phenyl hydrazine or ethyl cyanoacetate gave the corresponding heterocyclic compounds 4, 5 and 6 respectively. Treatment compounds 3a,b with cyanothioacetaimde furnished 3-cyano-4-(1,3-diphenyl-1H-pyrazol-4-yl)-6-phenyl/(2-thienyl)pyridine-2(1H)-thiones (7a,b). Reaction of 7a,b with chloroacetamide, p-methylphenacyl chloride, ethyl chloroacetate, chloro-N-(aryl)acetamides gave S-substituted methylthiopyridines 8a-g. Upon treatment of compounds 8a-g with sodium ethoxide in boiling ethanol, they underwent intramolecular Thorpe-Zeigler cyclization giving 2-functionalized 3-amino-4-(1,3-diphenyl-1H-pyrazol-4-yl)-6-phenyl/(2-thienyl)thieno[2,3-b]pyridines (9a-g). Compounds 9a,c were subjected to some sequence reactions to produce new pyrazolylpyridothienopyrimidines 10a-c, 11a,b and 13-16. |
| Philosophy Of Mathematics: About God Mathematician | Author : Adib Ben Jebara | Abstract | Full Text | Abstract :This research article is the continuation of the research article published in Ashese journal in December 2019
(http://ashese.co.uk/ajps-v3-issue-7/philosophy-of-mathematics-applying-the-theory-of-thoughts-as-mathematical-waves),that thoughts as mathematical waves implies that God is mathematician. That God is mathematician makes intellectualism the right philosophy. God did not create the Universe because one universe or another always existed.God is not all powerful because some infinites do not exist. As God is a mathematician, the afterlife is for studying and teaching. For half a century, the Western world has denied an intellectualismwhich made the greatness of the Western world.The succession is slow to come. |
| Philosophy Of Mathematics: About God Mathematician | Author : Adib Ben Jebara | Abstract | Full Text | Abstract :This research article is the continuation of the research article published in Ashese journal in December 2019
(http://ashese.co.uk/ajps-v3-issue-7/philosophy-of-mathematics-applying-the-theory-of-thoughts-as-mathematical-waves),that thoughts as mathematical waves implies that God is mathematician. That God is mathematician makes intellectualism the right philosophy. God did not create the Universe because one universe or another always existed.God is not all powerful because some infinites do not exist. As God is a mathematician, the afterlife is for studying and teaching. For half a century, the Western world has denied an intellectualismwhich made the greatness of the Western world.The succession is slow to come. |
| Philosophy Of Mathematics: About God Mathematician | Author : Adib Ben Jebara | Abstract | Full Text | Abstract :This research article is the continuation of the research article published in Ashese journal in December 2019
(http://ashese.co.uk/ajps-v3-issue-7/philosophy-of-mathematics-applying-the-theory-of-thoughts-as-mathematical-waves),that thoughts as mathematical waves implies that God is mathematician. That God is mathematician makes intellectualism the right philosophy. God did not create the Universe because one universe or another always existed.God is not all powerful because some infinites do not exist. As God is a mathematician, the afterlife is for studying and teaching. For half a century, the Western world has denied an intellectualismwhich made the greatness of the Western world.The succession is slow to come. |
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