Phyllodes tumor of the breast is an uncommon fibroepithelial neoplasm and accounts for less than 1% of the primary breast neoplasms. The median age of its occurrence is 40–50 years. It has been sub-classified histologically as benign, borderline or malignant. Accurate preoperative diagnosis and proper management are crucial for this tumor as it has a high potential for recurrence. The diagnosis of this rare tumor is based on clinical examination, radiology and cytology, but it is the histopathology which is the gold standard for it. Surgery is the treatment of choice, whereas chemotherapy, radiotherapy and hormonal therapy have got limited role so far. We report a rare case of recurrent malignant phyllodes tumor in a young nulliparous female, which is not the usual age group for this tumor.

Phyllodes tumor of the breast is an uncommon fibroepithelial neoplasm and accounts for less than 1% of the primary breast neoplasms. The median age of its occurrence is 40–50 years. It has been sub-classified histologically as benign, borderline or malignant. Accurate preoperative diagnosis and proper management are crucial for this tumor as it has a high potential for recurrence. The diagnosis of this rare tumor is based on clinical examination, radiology and cytology, but it is the histopathology which is the gold standard for it. Surgery is the treatment of choice, whereas chemotherapy, radiotherapy and hormonal therapy have got limited role so far. We report a rare case of recurrent malignant phyllodes tumor in a young nulliparous female, which is not the usual age group for this tumor.

Introduction: Malignancy of gall bladder is quite common. However, it cannot always be diagnosed only by clinical history and examination. We have evaluated diagnostic accuracy of USG-guided FNAC in GB mass. Material and Methods: 37 cases were included in this study. USG-guided FNAC was done. Result: USG-guided FNAC gave 93.5% sensitivity, 100% specificity and 93.5% diagnostic accuracy. Conclusion: USG-guided FNAC is a good adjuvant to clinical and radiological findings in diagnosing carcinoma of gall bladder.

Osteosarcoma is rare, accounting for less than 1% of adult malignancies and 3–6% at the pediatric age, with peak incidences in adolescence and after 60 years of age.1 The incidence of osteosarcoma in the bones of hand has been reported to be low, around 0.9%.1 We report a 37-year-old female patient who presented with swelling in the distal phalanx of ring finger of left hand since 3 months associated with pain. Imaging studies were consistent with a destructive lesion. Histological examination revealed osteoblastic osteosarcoma of phalanx.

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to several pathogens such as viruses, bacteria, parasites, and also tumor cells. IRF1 & IRF2 are interferon regulatory factorsq