Evisceration is a widely performed surgery in the pediatric population, the most common etiology for children is trauma and malignant retinal tumors. The procedure is safe and the complications are rare and often easily manageable. We report the case of a 10 years old male patient, who had undergone evisceration surgery of the right eye 2 years before his admission, following a penetrating ocular trauma. The trauma circumstances were reported as accidental knife perforation. The patient was hospitalized and beneficiated from sutures of the globe injuries, associated to parenteral and local fortified antibiotics treatments. The follow-up was marked by installation of chronic painful endophthalmitis that was managed with an evisceration and hydroxyapatite implant. Two years later, the ophthalmic examination revealed the presence of 2 conjunctival cysts underneath the prosthesis, with no exteriorization of the hydroxyapatite implant. A surgery was then performed with removal of the conjunctival cysts.

Introduction: Retinoblastoma is one of the leading cancers in children below 5 years, leaving an ocular defect after enucleation. The loss of an eye requires early replacement so that socket contraction is minimal, growth of surrounding tissues is less retarted and the patient may return to a normal social life. Primary placement (at the time of enucleation) of hydroxyapatite intraocular implants is done in order to prevent volume defi cit and increase motility of the prosthesis. Exposure of this implant is a common complication where the amount of exposure usually decides the treatment modality. Large exposures requires surgical correction whereas small exposures may be managed conservatively.

Purpose: To detect pathogenic mutations in cytochrome P450 family1 subfamily B polypeptide1 (CYP1B1) gene in nineteen sporadic Primary congenital glaucoma (PCG) cases and to identify patients lacking CYP1B1 mutations. Methods: CYP1B1 exon 2 and the coding part of exon 3 of 15 participants were amplified by Polymerase chain reaction and amplicons were sequenced by Sanger sequencing. Sequencing data was analyzed to identify the gene mutations or Single Nucleotide Polymorphisms SNPs. Results: Four previously reported PCG-associated CYP1B1 mutations (c.1159G>A; p.E387K, c.230T>C; p.L77P, c.1103G>A; p.R368H and c.1568G>A; p.R523K) were found in four patients out of the 15 fully ‘sequenced’ patients. Also, ten previously reported Single Nucleotide Polymorphisms and two novel noncoding variants were identified. Conclusion: The relatively low percentage of PCG patients having CYP1B1 mutations (4/15=26.6%) demonstrates that other known and unknown genes may contribute to PCG pathogenesis. Lack of CYP1B1 gene mutations in some patients stresses the need to identify other responsible candidates

Colobomas are genetic malformations due to lack of closure of the embryonic fissure. These are rare malformations that can sit at any level of the eye. Colobomas can be uni or bilateral, sporadic or hereditary. It may be associated with other ocular manifestations and extra-ocular malformations involving a general, clinical and radiological examination. We report the case of a 28 year old young man with no significant pathological history whose ophthalmological examination revealed a coloboma affecting the iris, lens and choroid.

Purpose: to identify new functional parameters that may help in the early primary open angle glaucoma (POAG) diagnosis. Materials and Methods: 40 subjects were enrolled: 20 healthy subjects and 20 POAG patients, all aged between 30 and 65 years, for a total of 79 eyes, including 40 healthy and 39 POAG. All subjects underwent microperimetric test, Nidek MP-1 (NAVIS, software version 1.7.6; Nidek Technologies, Japan) using Humphrey 10-2 pattern with manual polygonize of upper and lower hemifi elds. Mean hemifi eld sensitivity was evaluated. Results: Analysis reported signifi cant differences of mean retinal sensitivity of the upper hemifi elds between POAG and healthy subjects (p < 0.025), thus highly signifi cant. Equally signifi cant (p < 0.025) was the comparison of ratio (upper / lower hemifi eld) between the two groups. There was not statistically signifi cant difference of sensitivity of lower hemifi elds (p> 0.05). Conclusion: signifi cant difference was observed between healthy and POAG groups using Humphrey 10-2 vertical asymmetry index. Therefore, it appears to be an unprecedented microperimetric diagnostic tool.

Introduction: Bilateral thalamic infarcts are a rare occurrence and accounts for about 22 to 35% of all the thalamic infarcts. Purpose: We report a case of bilateral thalamic infarction and double depressor palsy secondary to infarction of artery of Percheron. Results: A 24-year-old lady with sudden onset of diplopia without other neurological involvement. On examination patient had double depressor palsy. Magnetic resonance imaging (MRI) revealed an occlusion of the Artery of Percheron with infarction of the thalami and part of the midbrain. Conclusion: Bilateral thalamic infarction with double depressor palsy is a rare manifestation and it should raise the suspicion of an Artery of Percheron occlusion.

We present a case with incomplete Vogt-Koyanagi Harada disease and coexistent unilateral optic disc pit. It is well-known that optic disc pits can present with intraretinal splitting and serous retinal detachment [1].

Lamellar or zonular cataract is a hereditary cataract that is transmitted in an autosomal dominant mode. The crystalline opacities are located at the level of the primary fibers in the embryonic nucleus. This cataract is usually bilateral and asymmetrical. Sometimes the whole nucleus can be affected causing a signifi cant decrease in visual acuity. We report the case of a 19-year-old patient who was consulting for a decrease in visual acuity. Ophthalmic examination revealed unilateral lamellar cataract.