Introduction: Vascular complications of infective endocarditis are frequent and severe. The aim of this study was to clarify the epidemiological, clinical and prognostic characteristics of these vascular damages and determine their associated factors.

Background: The age is an important prognostic factor in patients with acute myocardial infarction. To find no similar data in the Mexican population, it seeks to establish the characteristics and prognosis of older adults carried out mechanical reperfusion treatment. Methods and results: We carried out a retrospective analysis included a total of 1025 patients in the program code myocardial reperfusion treatment carried out, being the 15.3 % over the age of 75 years. The age range of 33 to 92 years. The mortality rate is increasing exponentially higher age (3.4 % for patients <= 54 years, 6.1% for 55 to 64 years, 9.2% for 65 to 75 years and 15.9 % for the >= 75 years, p<0,001) in patients older than 75 years, primary angioplasty is the preferred method of reperfusion (77.7 %), without finding in this group of patients, an increase in the cerebral vascular event ischemic or hemorrhagic. Over the age of 75 years who develop cardiogenic shock have a much higher mortality compared with the younger (17.6%, 28%, 33% vs 56%, p<0.001). Conclusions: Despite the different treatments of reperfusion, mortality remains higher in older adults, mainly by multiple comorbidities and a higher rate of ventricular dysfunction.

As patients with chronic kidney disease (CKD) and chronic heart failure (CHF) increase, there is concern about a future heart failure pandemic. Deterioration of renal function is an independent prognostic factor for CHF after decongestion. Interactions between renal disease and cardiac disease are increasing, including nephrosclerosis and heart failure with preserved ejection fraction (HFpEF), which are both derived from augmentation of central pulse pressure by age-related arterial stiffening. Thus, it is necessary to treat multiple underlying diseases of cardiorenal syndrome simultaneously. However, an effective therapeutic strategy for HFpEF has not been established. This review reconsiders the pathophysiology of chronic cardiorenal disease related to arterial stiffening from the viewpoint of central hemodynamics and explores treatment options