Abstract :Chronic kidney disease is defined as either kidney damage or GFR < 60ml/min/1.73 m2 Body surface area for = 3 months with or without evidence of kidney damage, irrespective of the cause. Dialysis is a procedure for taking away waste and extra water from blood, and is used mainly to provide an artificial replacement for the off tracked kidney function in people with renal failure. This study was attempted to compare the effect of Hemodialysis and Peritoneal Dialysis (continuous ambulatory type peritoneal dialysis) on Serum Albumin and Body mass index of patients of chronic kidney disease. Study was attempted in the department of biochemistry in SMS medical college, Jaipur with 60 diagnosed Chronic kidney disease cases (30 patients undergoing hemodialysis & 30 patients undergoing peritoneal dialysis) after all essential clearance was obtained, we measured serum level of serum albumin and Body mass index. Results-Albumin was significantly higher in CKD patients undergoing Haemodialysis compare to Peritoneal Dialysis where p values was<0.03 using unpaired student’s t-test. In this study we conclude, serum albumin forecast cardiovascular, and infection-related mortality in both PD and HD patients. However, the threshold at which risk for death increases varies by dialysis type. According to this study, dietary habits, nutritional status to recommended allowance ratio were low in PD patients compared to HD patient but body mass index was found higher in PD patients due to Volume expansion. It suggests more nutritional diet may be required for PD patients.