The frequency of association between systemic sclerosis and primary biliary cholangitis is 5-10% and usually the first manifests as a CREST syndrome [4, 5]. In limited systemic sclerosis, 8% of antimitochondrial antibodies and 9-29% anti-Ro antibodies have been reported [6]. Primary biliary cholangitis begins insidiously, frequent pruritus accompanied by fatigue, or that is accidentally discovered when performing a liver profi le that evidences high concentrations of alkaline phosphatase plus the presence of antimitochondrial antibodies [7]. In the case of our patient she only showed incoercible pruritus. It is also important to emphasize that our case is compatible with CREST syndrome, which was considered incomplete because it didn’t present calcinosis. The respective analysis found ANA and anticentrome antibodies positive.

The male Z-plasty necklift (MZPN) is a well described procedure [1-4], specifi cally used for men with severe aging neck changes who cannot be achieve a satisfactory aesthetic outcome with other necklift procedures that are performed through a submental incision. Other direct excision male necklift techniques have also been described [5-9]. The MZPN is not felt suitable for women because of the visible anterior neck incision which does not camoufl age well with thinner smooth non-hair bearing neck skin, and an elective long visible scar located here is generally considered socially unacceptable. However, for men with severe aging changes of the neck this procedure produces results with a very high level of patient and surgeon satisfaction. Furthermore, surgical morbidity is very low with rapid recovery, and can easily be performed in the office surgery suite with local anesthesia with or without light sedation.

Background: Candida is an ubiquitious organism causing superficial fungal infections that are commonly encountered in clinical practice. Total polyphenols determined in terms of catechol equivalents per 100g of pomace were higher in Citrus limetta (63-112 mg of catechol equivalents/100g pomace) as compared to Ananas comosus (22-86 mg of catechol equivalents/10.