Abstract :Ameloblastomas are odontogenic tumors characterized by a high recurrence rate. Here, an Ameloblastoma that recurred 25 years after the initial surgery is reported. The patient was a 77-yearold woman. About 25 years ago, she underwent surgery to resect a mandibular Ameloblastoma at another hospital. The recurrent tumor was resected a 20-mm diameter focus in the gingival/ submucosal soft tissue. The histopathological diagnosis was spindle cell/follicular Ameloblastoma. In the literature, there are a few reports of recurrences around 20 years after resection, but most of these involve hard tissue, such as the bone at a resection margin or a bone graft, so this case of a recurrence in soft tissue is considered rare. In the future, follow-ups may need to be conducted in units of around 20 years.