Abstract :The pigmented lesions in oral cavity or on skin have been a diagnostic challenge to the dermatologists and oral physicians alike. Many chair side investigations such as woods light, skin biopsy, diascopy, shave biopsy have been improvised to aid and facilitate appropriate diagnosis for such lesions. Diascopy has been long accepted diagnostic aid in clinical dermatology but ironically till date no exclusive data is available for use of diascopy in oral pigmented lesions. Through this clinical tip on diascopy in oral lesions, the author’s aims to invoke the interest of oral physician to provide high quality care to patients with pigmented mucosal lesions. This clinical tip includes the principle, technique and indications and interpretation of diascopy test in orofacial pigmented lesions.