Objective: To investigate the prevalence and distribution characteristics of yellow fever virus antibody in human serum from epidemic areas of Tianjin port in 2013 and assess the situation of yellow fever virus in different countries in order to provide evidence for the prevention and control of yellow fever virus. Methods: The people from epidemic areas were selected as study object. 260 samples were collected together with detailed personal information. Each sample contained 5 ml venous blood. ELISA was used to detect the yellow fever virus antibody. The dengue virus antibody and west Nile virus antibody were detected in positive samples. Statistical analysis was used to compare differences of the positive rates between different nationalities, gender, occupation, age, and entry time. Results: All respondents came from Africa and South America, the total positive rate of serum antibody to yellow fever virus was 25.38%. Of which, the positive rate of South American personnel was relatively high, up to 27.27%. There was no significant difference in positive rate between different genders. The >40 year old age group was the highest, up to 42%. The positive rate of labor workers was relatively high, up to 45.24%. In the time distribution, the positive rate of fourth-quarter entry personnel was relatively high, up to 31%. Conclusion: The yellow fever vaccination rate of people from epidemic areas in 2013 was low. These people pose a threat to public health security of china as a potential source of infection. There was a significant difference in the detection rate of yellow fever virus antibody among people with different ages and occupations.

Chromogranin A and pancreastatin are neuroendocrine tumor markers. A 69-yearold female presented for diagnosis and management of a potential neuroendocrine tumor related to nausea, vomiting, and diarrhea for over 40 years. Initial neuroendocrine tumor work-up only revealed a slightly elevated chromogranin A level. Computed Tomography (CT) of chest, abdomen, and pelvis did not find neuroendocrine tumors. Her pancreastatin levels were higher than upper limit of normal at one commercial laboratory with a pancreastatin assay developed in-house but entirely normal in another which used a validated assay. The patient in this case illustrates an often-neglected cause of false positive test result, namely, spurious assay. Clinicians need to critically analyze a given test result in the context of clinical history, physical examination findings, other biochemical test and imaging results, and histological evidence, and to determine if an unexpected test result is false positive.

Objective: To describe clinical and epidemiological characteristics of patients confirmed with brucellosis in the Cuban Hospital (Qatar) during 2014 to June 2016. Methods: Clinical and laboratory data were collected from the medical records of 41 confirmed cases of Brucellosis. Results: Patients were from six nationalities, predominantly Qatari (56.1%). Fever of prolonged course (85.7%), muscle and joint pain were the most common symptoms. 61% of patients had high titers in serology for Brucella melitensis or abortus, while 12.2% and 14.6% had positive blood culture and serology. The predominance of high figures for liver enzymes (AST and ALT) and Protein C-reactive were observed. Conclusion: The clinical and epidemiological characteristics would be a reference for clinicians and especially when provides care to patients from countries with active transmission of the disease

Becker Muscle dystrophy is a regressive orphan X-linked disease that will progress into hypotonia and muscle weakness involving the skeletal as well as the cardiac muscles, with increased CPK blood levels and hypertransaminasemia. Patients with Becker muscle dystrophy rarely present symptoms at early age. Here we present a patient with Becker dystrophy, increased ALT and marked digestive symptoms. The digestive symptoms were proven to be linked to a celiac disease that was overlooked due to the presence of the muscle dystrophy. It is not uncommon in areas with very high consanguinity rates to have a patient presenting two rare genetic diseases at the same time. The initiation of a gluten free diet helped improve the symptoms and the wellbeing of this patient.

Two placentas obtained of woman pregnancy at 32 at 39 years old with gestational ages of 37 and 41 weeks of pregnancy were classified as P1 and P2 respectively. Patient P1 with history clinic of three gestations, two caesarian, one abortion and 117 Kg of weight and P2 with seven gestations, 67 Kg of weight, without that history. Specimens were fixed and processed according H&E stain and the degenerative changes in the placental villi observed with light microscopy. Observations were done in base at necrosis, immaturity, fibrinoid change, edema, hemorrhage, infarcts, chorangiosis, syncytial knots, calcification, fibrosis, polymorphonuclears, changes in the wall of the vessels and intervillous thrombosis. P1 showed degenerative changes in syncytium and stromal region with increased deposition of fibrinoid, edema, tissue death, vessel-contraction, chorangiosis, calcification, infarcts and destruction of the organization of the villi. P2 with dilatation of vessels, infarcts, stem villi with degenerative changes in syncytium and stroma, edema and contracted vessels. Terminal and intermediate placental villi were seen destroyed and erythrocytes are expelled to the intervillous space. Chronic hypertension has provoked severe degenerative changes to the placental villi disorganizing the placental structure with high risk of the good fetal development.