In this work on celiac disease, the authors focus mainly on the most relevant historical aspects that have been patterning knowledge on celiac disease. Once more details of the disease through their symptoms have been known, a more rigorous profile of this pathology was made. Thus, the Celiac Diseases first was considered a chronic indigestion without relation to the type of food ingested, then it was found that it was based on an intolerance to gliadin and other similar proteins, later that it is an autoimmune disease. The important contributions of Areteo, Soriano, Gee, Herter, Dicke, Anderson, Marsh are reviewed and their contributions and research have helped indisputably the knowledge of the central aspects of the Celiac Disease. This paper does not want to obviate the work of Spanish physicians and researcher as Santiago Cavengt, Ángel Ballabriga, Manuel Suárez Perdiguero, Isabel Polanco nor the work of the international and national Celiacs societies and the Spanish “Ministry of Salud y Consumo”.

Introduction: Sexual education is a priority in the psychosocial development of people and there is a significant deficit both in the school and the Institutes and Universities, in the informative-preventive field, as in sexual counseling and in the intervention of Clinical Sexology and / or Sexual Medicine that are taught, already as indispensable subjects in the Faculties of Medicine of Europe, USA, Canada and Latin America. In Spain we have more than a decade with a Master of Sexology that is taught at universities (Almeria, Health Sciences (UAL, Seville, Extremadura) Other University as Camilo José Cela, (at the INCISEX, the Institute of Sexological Sciences ) has been teaching sexology for more than 4 decades, and today sex education occupies spaces in many schools and in many families.The physical and emotional need to touch us, to give us pleasure and intimacy, accompanies us from birth to We die, to all people, sexuality is reworked throughout a life. Objective: To value sexual education in our area. Method: Analysis of rights and duties in education applied to the sexual field in our country. The OMS. defines Sexual Health in 1975. The W.A.S. in the XIII World Congress of Sexology, (29.06.1997 establishes the Universal Declaration of Sexual Rights or Declaration of Valencia) and updates them in 2014. Results: There has been an increase in Spanish legislation in the field of sex education, however, an important deficit is still detected that logically limits the formation and development of people. For a National Sexual Health Plan, and implementation of the March 2010 Law. Organic Law 2/2010, of arch 3, on sexual and reproductive health and the voluntary interruption of pregnancy. https://www.boe.es/buscar/pdf/2010/BOE-A-2010-3514- consolidado.pdf Conclusions: Sexual education should be increased in schools, institutes and universities that facilitate the personal development of all people, from infancy to old age.

Introduction: Sexual education is a priority in the psychosocial development of people and there is a significant deficit both in the school and the Institutes and Universities, in the informative-preventive field, as in sexual counseling and in the intervention of Clinical Sexology and / or Sexual Medicine that are taught, already as indispensable subjects in the Faculties of Medicine of Europe, USA, Canada and Latin America. In Spain we have more than a decade with a Master of Sexology that is taught at universities (Almeria, Health Sciences (UAL, Seville, Extremadura) Other University as Camilo José Cela, (at the INCISEX, the Institute of Sexological Sciences ) has been teaching sexology for more than 4 decades, and today sex education occupies spaces in many schools and in many families.The physical and emotional need to touch us, to give us pleasure and intimacy, accompanies us from birth to We die, to all people, sexuality is reworked throughout a life. Objective: To value sexual education in our area. Method: Analysis of rights and duties in education applied to the sexual field in our country. The OMS. defines Sexual Health in 1975. The W.A.S. in the XIII World Congress of Sexology, (29.06.1997 establishes the Universal Declaration of Sexual Rights or Declaration of Valencia) and updates them in 2014. Results: There has been an increase in Spanish legislation in the field of sex education, however, an important deficit is still detected that logically limits the formation and development of people. For a National Sexual Health Plan, and implementation of the March 2010 Law. Organic Law 2/2010, of arch 3, on sexual and reproductive health and the voluntary interruption of pregnancy. https://www.boe.es/buscar/pdf/2010/BOE-A-2010-3514- consolidado.pdf Conclusions: Sexual education should be increased in schools, institutes and universities that facilitate the personal development of all people, from infancy to old age.

Introduction. Biogenic amines (BA) can be found in foods subject to fermentation, in considerable quantities can cause poisoning to the consumer. Objective. The aim of this study was to evaluated the effect of fermentation and the roasting on the production-degradation of BA of cocoa seeds. Methods. In a first phase (P1), under a completely randomized design, the role of fermentation on BA was verified by four treatments, inhibition of yeast growth; inhibition of bacterial growth; traditional fermentation and unfermented seeds. In a second phase (P2), through a repeated measure factorial design 3X2, six treatments were evaluated, product of the combination of two lactic acid bacteria (LAB) (L. plantarum, L. fermentum, L. plantarum + L. fermentum) and two concentrations of starter culture (106 CFU/g, 108 CFU/g) to investigate the effect of exogenous LAB in the production-suppression of BA. Results. In the P1, the presence of three AB of interest was confirmed, with putrescine being found in greater quantity (37 - 45.2 ìg/g). Histamine and tyramine were found in lower concentrations without effect of fermentation on AB production. The E2 showed an effect of the LAB in the production of putrescine, reaching values up to 41.1 ìg/g when the highest LAB concentration was inoculated during the fermentation. Histamine was reduced in the beans after roasting when L. plantarum was inoculated to 108 CFU/g. Conclusion. The exogenous LAB do not have a essential role in the production-degradation of AB during the fermentation of cocoa seeds.