Abstract :Abstract
Cancer continues to be one of the prime human threat diseases now a days, causes six million deaths around the world every year (WHO), the existing chemotherapeutic drugs such as doxorubicin, daunorubicin, bleomycin and cisplatin are inadequate and having adverse side effects with multiple drug resistance (MDR). The modes of action of chemotherapeutic are influencing both cancer and normal cells to some extent. As an alternative many natural entities for anticancer activity rooted from biological origins almost desert to the deep sea has been accounted, but it has a restriction of solubility and bioavailability. To conquer this impediment, emphasizing the nanovehicles for sustained and targeted delivery encrusted with active natural ‘payloads’ were advisable to improve the quality of cancer patient’s self-life. Biologically active compound functionalized metal can be employed as a nano-drug formulation for cancer therapy.