Abstract :Stem cells are wonderful biological gifts of nature for renewal and regeneration of cells and tissues as well as rejuvenation of organisms. They are naturally endowed with immense potential for self-renewal and differentiation of almost all types of cells, therefore, are able to perform repair of damaged tissues and maintain tissue homeostasis. This precise task of tissue homeostasis is accomplished by continuous secretion of various cell growth factors and replacement of damaged/ dead cells by proliferation of resident stem cells in the tissues. The damaged site of the tissue can also attract stem cells from other sites of the body.