Abstract :Abstract
The calcium (Ca2+) signaling proteins are activated by a transient increase in free resting intracellular free Ca2+ concentration and regulate numerous cell process including disease conditions. The neuronal Ca2+ sensor-1, calmodulin, Ca2+/calmodulin dependent protein kinases, and calcineurin are some of the important Ca2+ signaling proteins known to play an important role various organisms and in human diseases, and have the potential as drug targets.