Abstract :Abstract
The eye is a highly sensitive organ. Its physiology and anatomy leads to considering it as a highly protected organ. Effective therapy depends on designing of delivery system. Brain targeting through the ocular delivering system, is a formidable task. But now a day’s ocular delivery plays a promising approach towards brain targeting. The Scientist has been found, some alternative models for brain targeting. These delivering systems have the ability to overcome limitations of current therapy. Treating brain tumors are kind of difficult task due to their uncontrollable growth & poor prognosis. Chemotherapy, aggressive surgical & radiotherapy is resulting in harmful side-effects to the human body. Toxicity and adverse effects can be minimized via the brain targeted delivery system. This will tend to enhance the accumulation of drug in tumor region. The ocular delivering system becomes a new strategy for brain therapy. This review deals with recent strategies, approaches, its vision, future aspects, patents & challenges in brain targeting. It also gives further insight for improved therapies in treating brain disorders via ocular route.