Ovarian Remnant Syndrome: A Case Report |
Author : Leila Cristina Soares1*, Ricardo José de Souza1 and Jorge Luiz Alves Brollo2 |
Abstract | Full Text |
Abstract :Ovarian Remnant Syndrome (ORS) results from the presence of residual ovarian tissue after oophorectomy. The gold standard treatment for ORS is surgery. We report the case of a 44-year-old woman who presented with pelvic pain and was diagnosed as having ORS. She obtained relief after treatment with a gonadotropin-releasing hormone agonist and gabapentin. Avoiding surgery with its greater risks is desirable in ORS; however, more studies should be performed to assess the long-term effects of gabapentin. |
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The Effect of the Antioxidant Drug “U-74389G” on Uterus Congestion During Ischemia Reperfusion Injury in Rats |
Author : Constantinos Tsompos1*, Constantinos Panoulis2, Konstantinos Toutouzas3, Aggeliki Triantafyllou4, George Zografos3 and Apostolos Papalois5 |
Abstract | Full Text |
Abstract :Objective: This experimental study examined the effect of the antioxidant drug “U-74389Gâ€, on rat model and particularly in a uterus Ischemia Reperfusion (IR) protocol. The probable beneficial effect of that molecule was studied pathologically using mean Uterus Congestion (UC) lesions.
Materials and methods: 40 rats of mean weight 231.875 g were used in the study. UC lesions were evaluated at 60 min of reperfusion (groups A and C) and at 120 min of reperfusion (groups B and D), A and B without but C and D with U-74389G administration.
Results: U-74389G administration significantly decreased the predicted UC scores by 0.31 [without lesions] [-0.47 - -0.16] (p=0.0004). Reperfusion time kept non-significantly increased the predicted UC scores by 0.10 [without lesions] [-0.21- 0.12] (p=0.2845). However, U-74389G administration and reperfusion time together produced a significant combined effect in decreasing the predicted UC scores by 0.17 [without lesions] [-0.27 - -0.08] (p=0.0005).
Conclusion: U-74389G administration whether it interacted or not with reperfusion time, significantly short-term kept the UC lesions scores unaltered. |
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Molecular Diagnosis and Prenatal Diagnosis in Abelson’s Helper Integration 1 gene (AHI1) in a Family with Joubert Syndrome |
Author : Chen Biliang*, Li Yu, Xu Ying, Zhang Jianfang, Tang Xing, Song Tingting, Guo Fenfen, Xu Hui, Yan Feng and Wang Detang |
Abstract | Full Text |
Abstract :Fetomaternal Hemorrhage (FMH) occurs in 3:1000 live deliveries. The severity of the event depends on the rate and the size of the blood loss in relation to total fetal blood volume. Clinical findings range from pallor, respiratory distress, and hypovolemic shock to stillbirth or neonatal death. We report a clinical case of a newborn who suffered a severe fetomaternal transfusion, corroborated by the Kleihauer-Betke (KB) test, with favourable outcome. |
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Recurrent Miscarriage: A Review |
Author : Barrenetxea G1,2*, Ortuzar M3 and Barrenetxea J4 |
Abstract | Full Text |
Abstract :Human reproduction is characterized by its inefficiency. The loss of pregnancy at any stage can be a devastating experience and particular sensitivity is required in assessing and counseling couples with Recurrent Miscarriage (RM). Recurrent Miscarriage (RM) represents a clinical challenge for physicians not only because there are multiple possible etiologies, but also because the diagnostic testing is costly and time consuming. Despite several well-known etiologic factors, the cause of RM cannot be determined in almost 50% of cases. Multiple potential etiologies for RM have been described and, as a consequence, several recommendations with very different levels of evidence have been published regarding the evaluation and management of this condition. |
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