Background: Hypothyroidism can cause hypertension, hypercholesterolemia, cardiac dysfunction, and both hypo- and hypercoagulability; all of which are risk factors for stroke. Objectives: To explore the association between thyroid disease and occlusion of large vessels as well as functional outcome in patients with ischemic stroke.

Accumulating evidence suggests that the food and drink consumed by us have an impact on our mental and physical function. Food and food components, which exert physiological and mental effects are termed as ‘functional foods’ or ‘nutraceuticals’. Such foods are considered to offer sustained good health and protect against illness, disease and pathological ageing. Water constitutes 60-80% of the human body; however, it usually goes unnoticed as an important nutrient that can have an impact on mental performance in addition to physical performance

Keywords: Vascular Dementia; Ischemic Stroke; Vascular Risk Factors; Clinical Investigations; Comorbidities Introduction: Vascular dementia (VaD) is one of the most common causes of dementia in the elderly (those over the age of 65), with a variable presentation and unpredictable disease progression. Current evidence indicates that 25-30% of ischemic stroke patients are likely to develop either immediate or delayed vascular cognitive impairment, or VaD. The development of dementia following a stroke is determined by several factors

Focal cortical dysplasia (FCD) is a congenital abnormality of brain development where the neurons in an area of the brain failed to migrate in the proper formation in utero and is one of the important cause of intractable epilepsy in children and in adults. We are presenting a 11 years old female patient with intractable seizures since the age of 1 ½ years, Extra temporal complex partial in nature, on evaluation MRI brain showed Type IIb Focal Cortical Dysplasia (FCD), PET CT showed marked hypo metabolism in Right insular cortex and video EEG showed few epileptiform activity during wakefulness over Right fronto temporo parietal regions. Epilepsy committee meeting concluded to proceed with resection of Right frontal opercular FCD under EcoG monitoring with neuro navigation, IONM & image guidance. Patient underwent Right Pterional craniotomy and Micro surgical resection of the Right frontal opercular FCD under Monitoring. HPE suggested as Focal Cortical Dysplasia ILAE/PALMINI type IIB. Post operatively, on three months followup patient was seizure free.

Foreign bodies in the urinary bladder can produce a variety of storage and obstructive urinary symptoms and later lead to serious complications. It is very difficult to introduce long and flexible foreign bodies into male urinary bladder due to the peculiar anatomy of the urethra. We present the case report of a 29-year-old male patient who inserted a very long foreign body into his bladder for alleviation of symptoms of overactive bladder not responding to medications, which unfortunately led to further aggravation of his symptoms.

Background: Mechanical thrombectomy (MT) is an effective treatment for acute ischemic stroke with large vessel occlusions (LVO). However, MT also carries a risk of hemorrhagic complications (HC). In this study, we analyzed factors associated with HC at a single center, with particular attention to intraoperative factors. Methods: We identified 312 patients (193 males, 119 females) that underwent MT at our center. The average age was 75.2 years. Clinical and technical complications were retrospectively identified and related factors were extracted from surgical records and examined in relation to bleeding complications.

The second most common haematological malignancy, Multiple Myeloma (MM), is caused by the clonal proliferation of malignant plasma cells. With little side effects, Bortezomib, first proteasome inhibitor, increased response rates and overall survival in newly diagnosed and recurring patients of MM. While corticosteroids are known to result in several psychiatric manifestations, there are only a few reported cases of mental illnesses caused by Bortezomib accounted for in the literature. This article describes a 68-year-old man who has multiple myeloma. He has been stated as experiencing manic symptoms and is currently undergoing regular treatment with Bortezomib, Dexamethasone, and Cyclophosphamide.