Surgical Treatment in Bronchiectasis: Analysis of Our Patients | Author : Edvin Selmani, Fatmir Brahimi, Leard Duraj | Abstract | Full Text | Abstract :Background: Bronchiectasis is usually caused by pulmonary infections and bronchial obstructions. It is
still a serious problem in developing countries, as our country. We reviewed the morbidity and mortality
rates and outcomes of bronchiectasis surgical treatment.
Patients and methods: Between years 2000 and 2016, one hundred and seven (107) patients, sixty
nine (69) of whom female and thirty eight (38) male underwent pulmonary resection for bronchiectasis.
The mean age was 35years (range, 13–66 years). Mean duration of symptoms was 12 years.
Results: Symptoms were copious amount of purulent sputum in 84 patients, expectoration of foulsmelling
sputum in 72, haemoptysis in 21 and cough in all patients. The indications for pulmonary
resection were: medical therapy failure in eighty two (82) patients, massive haemoptysis in eighteen
(18) and lung abscess in seven (7) patients. The disease was bilateral in twenty seven (27) patients and
mainly confined in the lower lobe. Eighty six (86) patients had a lobectomy, 7 had a segmentectomy,
two patients right pneumonectomy. Operative morbidity was seen in 47 patients (43.9 %) and mortality
in two (2) patients. Follow-up was complete in 97 patients with a mean of 5 years. Overall, 78
patients were asymptomatic after surgical treatment; symptoms were improved in 24, and unchanged
or worse in 5.
Conclusions: Surgical treatment of bronchiectasis is more effective in patient with localized disease. It
is satisfactory with acceptable ratio of morbidity and mortality. |
| Predictive Factors and the Role of Traumatic Brain Injury in Stroke | Author : Basha E, Kuqo A, Djamandi P, Kruja J | Abstract | Full Text | Abstract :Background: Traumatic brain injury (TBI) is the leading cause of mortality and invalidity worldwide.
Objective: To explore whether traumatic brain injury may be a risk factor for subsequent stroke and to
evaluate the role of other risk factors correlated with TBI and stroke.
Methods: We analysed 643 patients presented in the emergency department of Trauma UHC, from
1stof June 2011 - 1st of December 2011. We evaluated the following factors: age, gender, and severity
of head trauma, type of head trauma, systemic hypertension, atrial fibrillation, and diabetes mellitus.
Results: During 1-year of follow upperiod 32 (4.97%) strokes occurred in TBI patients. The evaluation
was done in correlation with the other risk factors taken into account in the study.
Conclusions: The role of TBI is underestimated in the evaluation of stroke. This study demonstrated
that during the first year after TBI, 13.53 % of patients experienced stroke. After careful statistical correlations
with the selected co-morbidities, we found that the diagnosis of stroke was strongly related
with TBI. |
| Management of Explosions and Blast Injuries after Gërdec Tragedy, Albania | Author : Agron Dogjani, Engjellushe Jonuzi, Shkelzen Osmanaj, Fadil Gradica, Rustem Celami, Rifat latifi | Abstract | Full Text | Abstract :Background: In the last decade, the risk of terrorist attacks has increased largely almost worldwide. In
this setting, disaster response personnel must understand the unique physiopathology of injuries associated
with explosions and must be prepared to assess and treat the people injured in such tragedies.
The ammunition explosion in Gërdec, Vora, just 13 miles from the capital of Albania, Tirana, confronted
our country with a real human tragedy with severe casualties. The striking force of the two consecutive
explosions resulted in two consecutive earthquakes with respectively an amplitude of 9.2 and 2.5 on
the Richter scale.
Objective: To explain the classification of explosives and in connection with it to identify the major
types of explosive and blast injuries, and the management options in the cases of explosions and blast
injuries.
Material & Methods: Efforts to dismantle Albania’s stockpiles of obsolete munitions took a catastrophic
turn on March 15th, when a series of explosions occurred as crews were clearing out a storage depot
in Gërdec, on 15th of March 2008, at 12:15 AM hours. Gërdec is located 10 km northwest of the capital
of Albania, Tirana; near the national highway Tirana-Durres and at a distance of 3-4 km in air line from
National Airport. Data presented here were collected from the patients’ files in our Trauma UHC and
from the official reports from the different governmental offices.
Conclusion: The explosive and blast injuries now present a true modern epidemic disease that threaten
the very survival of the free world. A thorough understanding of detonation and blast dynamics by
the treating teams is required to better correlate the injury patterns presented. This is also critical for
revision of current multiple casualty protocols. It is up to the medical establishment to prepare suitable
protocols, coordinate manpower and secure medical resources to successfully handle such events. |
| Gender Related Differences in Reported Respiratory Symptoms | Author : Altin Habazaj, Holta Tafa, Donika Bardhi, Hasan Hafizi | Abstract | Full Text | Abstract :Background: Physiological research on dyspnea has provided some information on how sex differences
in lung and airway size can influence the experience of dyspnea during exercise; however, there is still
a knowledge gap with regard to sex-related differences in other respiratory symptoms, including cough
and sputum production.
Objective: The objective of this analysis was to assess sex related differences in reported objective
symptoms using data from the population-based Burden of Obstructive Lung Disease (BOLD) study in
Albania.
Method: Males and females with impaired lung function may experience the same symptoms but perceive
and/or report them differently. In this analysis were included 997 responders who had completed
the core questionnaire, which included data on respiratory symptoms using the following questions:
“Do you usually cough when you don’t have a cold?” and “Do you usually bring up phlegm from your
chest, or do you usually have phlegm in your chest that is difficult to bring up when you don’t have
a cold. Chronic was defined as three months or more per year. Data used were drawn from the final
report for Albania provided by BOLD team.
Results: Overall, male gender was associated with increased odds for reported chronic cough at any
group age [Total: 14.7 (2.3) vs. 6.6 (0.9)]. This difference is very much reduced in the group age 70+
years old [25.8 (8.2) vs. 21.3 (6.8)]. In the contrary when we used the estimated population prevalence
of chronic cough by pack-years and gender, female gender was associated with increased odds
for reported chronic cough especially in the 10+ pack-years groups [50.4 (11.0) vs. 12.2 (8.3) in 10-20
pack-years and 29.0 (5.5) vs. 26.0 (3.3) 20+ pack-years] indicating a increased smoking susceptibility of
female gender. In contrast, female gender was associated with decreased odds for reported phlegm.
Even for the same pack-years of smoking, female gender is associated with decreased odds for reported
chronic phlegm [0 vs. 7.1 (8.6) in 10-20 pack-years group; 0 vs. 15.4 (3.0) in 20+ pack-years group].
Conclusions: Physicians need to recognize that although a female may not report chronic sputum or
phlegm production and a male may not report chronic cough, a diagnosis of Chronic Obstructive Pulmonary
Disease should still be considered as symptoms often are the first step to a diagnosis of underlying
airway disease. |
| Management of C4-C5 Fracture with Approach 360° Without the Spinal Instrumentation | Author : Erion Spaho, Artid Lame | Abstract | Full Text | Abstract :Introduction: Usually, cervical pedicle screw fixation has been considered too risky for neurovascular
structures. The purpose of this case report is to present a young male patient who suffered a C4-C5
fracture after a motor vehicle accident treated with a 360°surgical approach without spinal instrumentation.
Case report: A young male patient suffered a motor vehicle accident driving the vehicle without seat
belt. Instantly after the accident he reports about severe neck pain, inability to move his left extremities,
difficulty moving his right extremities, burning pain. All patients had various degrees of cord injury,
and they were classified according to the American Spinal Cord Injury Association (ASIA) Impairment
Scale and Denis classification.
Results: We present this young patient, where the selected surgical approach without using spinal
instrumentation resulted has favorable outcome.
Conclusion: Surgical options regarding to cervical spine fractures include stabilization and decompression
with and without spinal instrumentation. Carefully selected cases may be treated safely without
instrumentation avoiding potential complications of spinal instrumentation such pseudoarthrosis, instrumentation
failure, infection, etc. |
| Homocysteine and Risk of Premature Coronary Heart Disease | Author : Lutfi Zylbeari, Sihana Ahmeti Lika, Nasir Behxheti,Mirlind Behxheti, Zamira Bexheti, Jetmire Jakupi- Alimani, Hanife Ahmeti, Ferizate Dika Haxhirexha, Ledia Kaci, Kastriot Haxhirexha | Abstract | Full Text | Abstract :Background: Homocystinuria is a rare autosomal recessive disease complicated by early and aggressive
occlusive arterial disease. This may be related to the grossly increased homocysteine concentrations
seen in this disease. More recently, milder hyperhomocysteinemia has been proposed as an independent
risk factor for coronary artery disease. Cardiovascular disease (CVD) is among the diseases with
multiple contributing factors, hence making it difficult to pinpoint a particular factor alone. The main
factor that is of relevance to this study is homocysteine. Coronary artery disease is the narrowing or
blockage of the arteries and vessels that supply oxygen and nutrients to the heart (1, 2). CVD are the
major cause of morbidity and mortality worldwide. Obesity, HTA, Diabetes mellitus, hypercholesterolemia
and smoking have been recognized as major risk factors for CVD.
Aim: Aim of this paper is to examine concentrations of Hcyt and lipid profile in patients with CVD and
positive personal history for CVD, comparing them with the control group composed from healthy
individuals. Our study aimed to verify the role of Homocysteine as new indipendent risk factor on the
onset of early atherosclerosis and atheromateous processes in coronary arteries in patients with CVD.
Materials and methods: The results obtained represent the average value earned once every three
months in the 3 year period. 5ccm serum with a few heparin spots was sent to the Clinical Laboratory
of the University Clinic of Skopje.
Results: The results obtained from patients with CVD and control group are presented in the following
text, where a statistically significant difference was observed for p <0.0001 between the parameters
obtained by patients with CVD compared to the control group. In Concentrations of homocysteine
and lipids in patietns with CVD compared to the control group showed satisticaly significant difference
with p<0.0001, expected results and verified in many other multicentric studies. These facts show
that raised Hcyt have more immpact on the onset of CVD .When Hcy levels are in blood, the activity
of cystathionine-synthethasae enzyme is raised. It is believed that this enzyme plays vital role on the
metabolism of Hcyt. Recent years a lot of studies have been made on the effect of hyperhomocysteinemia
and its impact on the onset of coronary and all have verified that hyperhomocysteinemia is a
significant parameter for the onset of early artherosclerosis of coronary and CVD(6,7,8).
Conclusions: In above mentioned cases it is recom-mended substi-tuive therapy with folic acid, pyridoxine,
vitamin B12, vitamin E and other antioxidants which is found that have effect on prevention of premature artherosclerosis in patients with CVD and raised Hcyt: acute myocardial infarction,CARB,
angina pectoris. PTCA, Stenting and prevention of stroke. |
| Intraperitoneal Amikacine Provoked Perceptive Deafness in CAPD - Continuous Ambulatory Peritoneal Dialysis Patient | Author : Lutfi Zylbeari, Sihana Ahmeti Lika, Mirlind Behxheti, Zamira Bexheti, Jetmire Jakupi-Alimani, Hanife Ahmeti, Ferizate Dika Haxhirexha, Ledia Kaci, Kastriot Haxhirexha, Nasir Behxheti | Abstract | Full Text | Abstract :Peritonitis (P) is the main complication and primary limiting factor in the extension of continuous ambulatory
peritoneal dialysis(CAPD) in developing countries, because of exposure to potential external
contamination, especially in people with unsatisfactory hygiene habits.We will present a case of peritonitis
in 62 years old woman after the first three months of CAPD treatment. The peritoneal infection
is confirmed by cloudy fluid with increased WBC in the dialysis solution (2300..1300..1100 cells/cmm;
polymorphonuclears between 60% to 80%), augmented fluid protein content(cca.2.4 g/l), presence of
microorganisms and symptoms of acute peritoneal infection(isolated Enterobacteria species, abdominal
pain and diarrhoea). The peritonitis was treated following the Oreopoulos group’s recommendations1
and after a report of the sensitivity of the isolated Enterobacteria, with appropriate antibiotic
(Amikacine) in recommended intraperitoneal dose. Three days after successful treatment of peritonitis,
the definite deafness is developed. |
| Cezarean Hysterectomy, A lifesaving Procedure that Albanian Obstetricans Must Be Familiar With | Author : Leon Kaza, Senad Halluni, Rustem Celami, Zef Delia | Abstract | Full Text | Abstract :Cezarean Hysterectomy refers to emergency peripartum hysterectomy - EPH, which is performed as a
life saving procedure in cases of continual obstetric hemorrhage secondary to uterine atony, uterine
rupture, placental disorders, fibroids, and lacerations during cesarean section - CS or vaginal parturition.
Emergency peripartum hysterectomy - EPH, although rare in modern obstetrics, remains a lifesaving
procedure in cases of severe hemorrhage. In contemporary obstetrics, overall incidence of severe
postpartum hemorrhage was reported to occur in 6.7/1,000 deliveries worldwide. It is one of the
leading causes of maternal mortality and morbidity and represents the most challenging complication
that an obstetrician will face. The incidence of peripartum hysterectomy in the literature is reported as
0.24, 0.77, 2.3, and 5.09 per 1,000 deliveries by many authors mentioning a few; Sakse et al., Whiteman
et al., Bai et al., and Zeteroglu et al., respectively. Nevertheless, there is a lack of Albanian data
on EPH. To our knowledge, there is no Portuguese information on postpartum hemorrhage and EPH,
which does not mean that we do not have suc obstetrical complication and therefore such emergency
intervention. This paper’s intention is to bring awareness of such catastrophic obstetrical complication
especially in young primigavida and primipara women. |
| Pulmonary Rehabilitation - PR | Author : Dh. Argjiri, S. Bala, F. Gradica, A. Menzini, L. Agolli, V. Miha, V. Selmani, O. Nuredini, Y. Vakeflliu | Abstract | Full Text | Abstract :Chronic respiratory diseases are associated with severe, not only pulmonary, but also systemic damage
such as dysfunction of peripheral muscles, dysfunction of respiratory muscles, nutritional disorders,
cardiac injuries, skeletal disorders, sensory debilities, and psychological dysfunction. Mechanisms of
these injuries are many and different. Pulmonary recovery (PR) is an integral part of clinical therapy in
patients with chronic respiratory disease who continue to be symptomatic or continue to have pulmonary
function depression, regardless of standard medical treatment. |
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