Abstract :Pancreatico-duodenectomy has been the main procedure for patients with malignant and benign
diseases. Pancreatic anastomosis remains the Achille’s heel. Two types of pancreatic anastomosis
have been gained favor in recent years: Pancreatico-gastrostomy versus Pancretico-jujenostomy. In
both techniques there are still many others modified technique. In this review, we analyzed various
types of anastomoses to underline which is the major safe anastomosis with good results.