Background In women, peritoneal cancer is commonly associated to epithelial ovarian cancer. Ovarian peritoneal carcinomatosis patient survival appears to be better in comparison to other peritoneal Malignancies, e.g., colorectal neoplasms or mesotheliomas. Here, we aim to analyze the value of CA125, CEA, CA125/CEA ratio (CCR) tumor markers as preoperative tools for the diagnosis ovarian cancer. Material and Methods: From 2005-2008, we recruit prospectively patients admitted to the Navarre Hospital Complex Gynecological service with peritoneal carcinomatosis and suspicion of ovarian cancer origins. The final diagnosis of ovarian cancer carcinomatosis or other malignancies was obtained through Biopsy or cytology. CA 125, CEA and CCR were determined from preoperative venous blood Samples. We compared the tumor markers values between groups of ovarian cancer carcinomatosis and non-ovarian cancer carcinomatosis and calculate the receiver operating curves (ROC) for CA 125, CEA and CCR. Results From 250 patients with suspicion of having ovarian peritoneal carcinomatosis, only 86.4% of the Cases were finally diagnosis of ovarian cancer. Sensitivities of CA125 > 35 mg/dL, CEA < 5 ngr/mL, and CCR > 25 were 95.5%, 91.9%, and 93.6% with specificities of 4.6%, 40.9% and 40.0%, respectively. ROC displayed poor performance for CA125 and CEA for detecting ovarian peritoneal carcinomatosis patients (area under the curve (AUC): 0.69 and 0.63, respectively) while ROC analysis of CCR showed better results (AUC: 0.74). Conclusions: CCR is somehow useful to differentiate between ovarian and non-ovarian peritoneal carcinomatosis patients in comparison with CA125 and CEA alone, although without sufficient specificity for improving the differential diagnosis.

Objective: to evaluate the impact of pre-gestational maternal age and body weight on the outcome of IVF in women with PCOS. Design: a retrospective study on women with PCOS undergoing IVF. Methods: Medical records of 200 known cases of polycystic ovary syndrome women treated in a third level referral center by the same therapeutic protocol were evaluated retrospectively. Demographic data, maternal body mass index, hormonal profile (LH, FSH, estradiol, anti-mullerian), IVF cycle parameters and outcome were documented. Patients were classified to three groups based on their body mass index (Normal: 18.5-24.9, overweight: 25-30, obese=30). IVF cycle parameters and outcome were compared in these 3 groups. Effect of age was also evaluated by comparing the results in patients aged <35 and =35. Results: Mean age of patients was 32.5 (±5.2). 72 patients had normal BMI, 85 patients were overweighed and 43 cases were obese. Baseline hormonal profile was similar in 3 groups. Total dose of administered FSH were similar in 3 groups. Number of retrieved oocytes was statistically significant higher in patients with BMI>30 but the number of mature oocytes and number of embryos were statistically lower in this group. Size of follicles showed no statistically significant difference in 3 groups. Clinical pregnancy rate was statistically significant lower in patients with BMI>30 kg/m2 and age>35 years old. Conclusions: BMI>30 and age >35 years old has a statistically significant negative impact on IVF success rate.

In Indonesia target of exclusive breastfeeding is 80% and this target is very difficult to accomplish. The scope of exclusive breastfeeding in West Sumatera (75%), in Padang (70.7%) and in the work area of Andalas Health Center (55.17%). This study aim is to determine factors associated with exclusive breastfeeding in the work area of ??Andalas Health Center. This type of study is analytic with cross sectional design.The participant of this study is 90 mothers who have infants 6-12 months in the work area of Andalas Health Center. Sampling was proportional random sampling. Data collected using questionnaires. Data analysis using univariate and bivariate with chi square test and significant if p value < 0,05. The study showed exclusive breastfeeding (21,1%), mother have a good knowledge (48.9%), secondary education (51.1%) , unemployed (65.6%), not having breast problem (51.1%), and interested in infant formula promotion (57.8%). The results of bivariate analysis showed a significant relationship between education (p=0.048) and breast problems (p=0,000) and no significant relationship between work (p=0.98) with exclusive breastfeeding. There is a tendency all mothers who have less knowledge and interested in infant formula promotion to not exclusive breastfeeding From the result of this study it can be conclude there is a significant relationship between education, and breast problems with exclusive breastfeeding, no significant relationship between work and exclusive breastfeeding, there is a tendency all mothers who have less knowledge and interested in infant formula promotion to not exclusive breastfeeding. For the next research can add other variables, for health workers to more diligent give counseling and for the community to follow more counseling.

Purpose: The purpose of the study was to evaluate the effectiveness of wet-cupping therapy (CT) on menopause specific quality of life (MENQOL). Methods: This study was conducted with randomized controlled pretest, and posttest method between July 2015 and July 2016 at a Gynecology Outpatient Clinic of University Hospital in Ankara, Turkey. Intervention group (n=30) received wet CT while control group (n=30) did not receive any therapy. Both groups were measured quality of life using MENQOL scale before and two weeks after wet CT. Results: The women’s age ranged from 45 to 60 years. Baseline characteristics were similar in the both groups. Women treated with wet CT showed significant improvements in their vasomotor, physical and sexual symptoms (p<0.001). No significant effect was found for pshysco-social area (p>0.05). No adverse effects were recorded after treatment. Conclusion: Wet CT can be considered as an effective method for reducing of menopausal symptoms. In conclusion, this study provides preliminary data on the effectiveness of various symptoms in postmenopausal period. However, further with larger sample size evidence-based trials are needed in order to confirm these results for improving MENQOL.