Introduction: Data provided by the “Mina Minovici” National Medico-Legal Institute Bucharest (Romania) demonstrate that most suicidal acts occur in Bucharest, followed by Satu Mare County and Harghita County. According to the 2021 census, more than one-fifth of Bihor County’s population is of Hungarian ethnicity. Material and methods: We conducted this study to compare suicidal acts between Romanians and Hungarians. Data were collected from the Bihor County Medico-Legal Service over a time interval from August 1, 2022, to July 31, 2023. Results: We found that most suicidal behaviors occurred in men, with an average age of 52 years. More than half of those who committed suicide were Hungarian. However, most women involved in suicidal acts were Romanian. Hanging was identified as the most common method of suicide. Conclusions: Although Hungarians represent only one-fifth of the total population in Bihor County, the study indicates that this ethnic group is more susceptible to suicide compared to Romanians.

Introduction: Colorectal cancer is the third most prevalent malignant tumor and the second leading cause of mortality, following bronchopulmonary cancer. The aim of our study was to evaluate demographic, clinical, and paraclinical data in patients with colorectal cancer, to find prognostic markers. Materials and methods: We conducted a retrospective observational study, including 204 patients with colorectal cancer who were admitted in the Clinical Emergency Hospital of Bucharest, from January 1, 2022, to January 1, 2024. Results: We identified a slight male predominance (54% versus 46%) and an average age of 67 years. However, a significant percentage of patients were diagnosed with colorectal cancer before the age of 50 years (11%). Regarding harmful behaviors, 24% of patients were smokers, and only 2.5% confirmed chronic alcohol use. The most common comorbidity of patients in our study was hypertension (65.7%), followed by obesity (43%) and diabetes (24%). The sigmoid colon was identified as the predilection location of colorectal cancer through endoscopic evaluation. The most common histopathological type was NOS adenocarcinoma (76.5%), followed by mucinous adenocarcinoma (16.7%). Most patients (77%) had moderately differentiated tumors (grade G2). The in-hospital mortality rate was 2.5%, and the average duration of hospitalization was 14.51 days. Conclusions: It is imperative to raise public awareness regarding the risk of colorectal cancer, to encourage the adoption of a healthy lifestyle and to facilitate the implementation of novel strategies to manage this condition.

Introduction: Liver cirrhosis (LC) represents a major public health problem, with high morbidity and mortality rates. Materials and methods: We conducted an observational, descriptive, retrospective study in which we included 198 patients with LC hospitalized in the Clinical Emergency Hospital Bucharest over a period of 2 years. They were divided into two primary groups: group A (83 patients with CH who had an infectious complication) and group B (115 patients with LC who did not have an infectious complication). Results: The predominant etiology of LC was excessive alcohol consumption, followed by viral infections, specifically hepatitis C virus and hepatitis B virus. The primary factors that contributed to the development of infectious complications were the presence of ascitic fluid, hypoalbuminemia, and a personal medical history of chronic kidney disease. The main infectious complications identified were bronchopneumonia (39%), urinary tract infections (27%), bacteremia (24%), Clostridioides difficile colitis (7%), spontaneous bacterial peritonitis (2%), and pleural empyema (1%). The average hospitalization duration and mortality rate were both twice as long for patients in group A as they were for patients in group B. Conclusions: In summary, infectious complications are a significant cause of morbidity and mortality in patients with LC and necessitate multidisciplinary management.

Introduction: In recent decades, infections caused by Pseudomonas aeruginosa and Acinetobacter baumannii have also occurred outside the intensive care unit (ICU), affecting patients with comorbidities in the community. Most of the nonfermenting Gram-negative bacilli (NFGNB) cause nosocomial bloodstream infections, particularly in debilitated and immunocompromised hosts. Our study aimed to find out the antibacterial susceptibility patterns of NFGNB isolates in the clinical samples. Materials and methods: The study included all NFGNB isolates from various clinical samples that the clinical microbiology laboratory received from inpatients and outpatients at Mahatma Gandhi Medical College and Hospital in Jaipur, Rajasthan, India. Routine microscopy of samples was done. We performed Gram staining on all samples, with the exception of urine. We inoculated all clinical samples on blood agar and MacConkey agar, then incubated them at 37°C for 18-24 hours. Colony characteristics were observed. All organisms that generated pale or colorless colonies on MacConkey agar and exhibited Gram-negative bacteria upon Gram staining of the colony were classified as non-fermenting Gram-negative bacteria (NFGNB) and subsequently identified using the VITEK-2 compact system. Results. We identified 879 NFGNB isolates from a total of 10,707 clinical samples. Of these, 415 (47.21%) were Pseudomonas aeruginosa and 378 (43.2%) were Acinetobacter baumannii. The majority of isolates were from males in the age group of 61-70 years (13.76%), followed by the age group 41-50 years (12.85%). Pseudomonas aeruginosa was most commonly isolated from pus swab (13.42%), and Acinetobacter baumannii was isolated most commonly from endotracheal secretions (21.4%). Conclusions. Increasing antibiotic resistance will lead to challenges in managing all NFGNB unless appropriate measures are implemented and novel medications are developed. In order to prevent the spreading of resistant Pseudomonas aeruginosa and Acinetobacter strains, infection control measures should be taken, clinicians and laboratory workers should cooperate during antibiotic use, and hospital hygienic rules should be observed.

Introduction: In recent decades, infections caused by Pseudomonas aeruginosa and Acinetobacter baumannii have also occurred outside the intensive care unit (ICU), affecting patients with comorbidities in the community. Most of the nonfermenting Gram-negative bacilli (NFGNB) cause nosocomial bloodstream infections, particularly in debilitated and immunocompromised hosts. Our study aimed to find out the antibacterial susceptibility patterns of NFGNB isolates in the clinical samples. Materials and methods: The study included all NFGNB isolates from various clinical samples that the clinical microbiology laboratory received from inpatients and outpatients at Mahatma Gandhi Medical College and Hospital in Jaipur, Rajasthan, India. Routine microscopy of samples was done. We performed Gram staining on all samples, with the exception of urine. We inoculated all clinical samples on blood agar and MacConkey agar, then incubated them at 37°C for 18-24 hours. Colony characteristics were observed. All organisms that generated pale or colorless colonies on MacConkey agar and exhibited Gram-negative bacteria upon Gram staining of the colony were classified as non-fermenting Gram-negative bacteria (NFGNB) and subsequently identified using the VITEK-2 compact system. Results. We identified 879 NFGNB isolates from a total of 10,707 clinical samples. Of these, 415 (47.21%) were Pseudomonas aeruginosa and 378 (43.2%) were Acinetobacter baumannii. The majority of isolates were from males in the age group of 61-70 years (13.76%), followed by the age group 41-50 years (12.85%). Pseudomonas aeruginosa was most commonly isolated from pus swab (13.42%), and Acinetobacter baumannii was isolated most commonly from endotracheal secretions (21.4%). Conclusions. Increasing antibiotic resistance will lead to challenges in managing all NFGNB unless appropriate measures are implemented and novel medications are developed. In order to prevent the spreading of resistant Pseudomonas aeruginosa and Acinetobacter strains, infection control measures should be taken, clinicians and laboratory workers should cooperate during antibiotic use, and hospital hygienic rules should be observed.

Introduction. Venous thromboembolism is the second leading cause of mortality in cancer patients. Patients with malignant conditions have a ninefold increased risk of thrombotic complications, and approximately 20% of patients with venous thromboembolism also associate cancer. The aim of our study was to determine the incidence and predictive factors for thromboembolic complications in patients with digestive cancers. Materials and methods: We conducted a retrospective study over six years, including 200 patients hospitalized in the Clinical Emergency Hospital of Bucharest, Romania, with digestive malignancies and thromboembolic complications. Results: The prevalence of venous thromboembolism among patients with malignant digestive tumors was 9.2%. The average age of these patients was 66 years. The malignancies with the highest incidence of thrombotic complications were pancreatic cancer, colorectal cancer, hepatocellular carcinoma, and gastric cancer. Histologically, all cancers were identified as adenocarcinoma, with 70% of patients exhibiting poorly differentiated tumors, and advanced tumor stages were observed in all cases. The most prevalent thrombotic complication was portal vein thrombosis, followed by deep vein thrombosis and pulmonary thromboembolism. The in-hospital mortality rate of these patients was 23.5%, while the 5-year mortality rate was 82.5%. Conclusions: We propose, as a future research direction, the enhancement of approaches to evaluate the risk of venous thromboembolism and discovery of novel biomarkers with a predictive role in patients with malignant tumors.

Persistent inflammatory syndrome is a frequently encountered and challenging condition in internal medicine. In cases when a definitive diagnosis is not established, this disease necessitates a thorough diagnostic approach to rule out infections, autoimmune disorders, and cancers. Case presentation: We present the case of an asymptomatic patient hospitalized with a significant inflammatory syndrome, in whom initial infection screening failed to reveal any diagnosis that might account for the biological abnormalities. In the lack of a diagnosis and the persistence of the inflammatory condition despite broad-spectrum antibiotic therapy, computed tomography examination of the chest, abdomen, and pelvis with contrast substance was performed, which identified a lung lesion with malignant features. The diagnostic management continued by bronchoscopy, bronchoalveolar lavage, and cytological, bacteriological, and molecular examinations, which revealed the presence of Mycobacterium tuberculosis. Conclusions: This case contributes to the understanding of tuberculosis as an “oncologic mimic” in cases of unexplained prolonged inflammatory syndrome, underscor the value of rigorous diagnostic approaches in atypical presentations and emphasizing the diagnostic vigilance required in patients with risk factors for this infectious disease.