This article introduces the mathematical modeling method and its important role in the field of biomedicine. Combining practical problems such as DNA sequence classification and infectious diseases, it explains the establishment and application of mathematical models, and introduces the specific steps of mathematical modeling in biomedicine. It also specifically introduces: DNA sequence classification model, infectious disease model, curative effect evaluation model, deterministic model and randomness model, and promotes in-depth research on biomedical mathematical modeling methodology.

The purpose of this case study was to investigate the healing capabilities of low-frequency ultrasound therapy to heal chronic painful ulceration. In this case, a 61-year-old African American female with a past medical history of hypertension, chronic venous insufficiency, and ovarian cancer on chemotherapy presented to the clinic complaining of a painful chronic ulceration to the left ankle. The patient attributed the re-ulceration of this chronic wound to her current chemotherapy treatment drug doxorubicin. After the initial consultation, patient therapy that recommended was ultrasound therapy due to the patient stating the lesion was too painful for frequent sharp debridement in the clinical setting even when utilizing a topical anesthetic. The recommended interval treatments included a seven-minute session to the wound three times a week over a period of nine months. There were noted changes in the appearance of the wound base after the first week of therapy and changes in the size by the second week of therapy. Throughout the treatment regimen, the patient’s pain tolerance to the wound improved as well. After nine-month, there was noted complete healing of the tissues without any complications. In conclusion, ultrasound therapy often referred to as MIST therapy can be a useful device to heal chronic painful wounds in immunocompromised patients when therapy options are limited.

The study examined the perception of Human Kinetics (Physical Education) and Engineering (Technology) Education, teachers on health safety practice skills: Legal liabilities and tort Administrative Agenda. These two fields of academic disciplines are prone to accidents/injuries during practical classes, in workshops and physical education (sports) activities arenas. Some of such accidents may be in the magnitude that parents or guardians may decide to seek redress in a competent law court. Yet some teachers in these areas of academic endeavour may still perceive such incidences as an act of God, hence they may not anticipate any legal consequences emanating therefrom. To this end, the researchers of this study, purposively selected a total of 102 teachers in these two areas of academic discipline, at the rate of 17 teachers from departments of Human Kinetics (Physical education) faculty of education and departments of electronics computer engineering (faculty of engineering) of these tertiary institutions: Federal College of Education (Technical Asaba Delta State), Federal College of Education (Technical Umunze Anambra State), Anambra State College of Education (Nsugbe Anambra State), University of Nigeria Nsukka and Odumegwu Ojukwu University Uli. The descriptive research design was used for the study. while the questionnaire fashioned after that of Likert was used as the instrument for data collection, which was pilot – tested on academic staff in same academic disciplines of Ebonyi State University Abakaliki, which did not form part of the study area, and yielded a reliability index of 0.81. Which therefore was considered adequate for the study. Data collected was analysed using chi-square inferential statistics tested at 0.05 significance level. All the 2 hypotheses tested were rejected. Hence, it was concluded that though these categories of teachers in the two academic disciplines under study, are aware of the legal implications that could arise as a result of accidents resulting from non-judicious practice/application of health safety skills during practical lessons, yet not enough Health safety practice skills could be seen being meticulously adopted to prevent accidents. Based on the findings of the research study recommendations were made.