Objectives: to assess voice changes of patients after thyroidectomy without inferior and superior laryngeal nerves injury according to the intraoperative neuromonitoring. Material and methods: This monocentric study included all patients who underwent thyroidectomy with laryngeal nerves neuromonitoring between September, 2018 and December, 2019. The voice assessment was performed 1 month before and 3 months after surgery. It was both subjective (with Voice Handicap Index 10 and GRBAS scale) and objective (Dysphonia Severity Index). Voice was considered impaired if there was an increase = 4 points of the Voice Handicap Index 10 score or = 1 point of the GRBAS scale score or a decrease = 2 points of the Dysphonia Severity Index score between the two vocal assessments. A composite score was created, combining both subjective and objective scores. Predictive factors of altered voice were seek. Results: Fifty-nine patients were analyzed. Mean Voice Handicap Index 10 varied from 3.39 ± 5.40 to 2.90 ± 5.29 (p = 0.62) before and after the surgery respectively, mean GRBAS from 0.64 ± 0.76 to 0.73 ± 0.85 (p = 0.57) and mean Dysphonia Severity Index from 8.47 ± 1.15 to 8.31 ± 1.03 (p = 0.42). Voice impairment composite score identified 14 patients with an impaired voice (23.7%). Age =65 years, preoperative Voice Handicap Index 10 score = 3 and thyroidectomy past history were independent risk factors of voice impairment. Conclusions: the voice quality 3 months after thyroidectomy was not significantly subjectively and objectively changed compared to before thyroidectomy. When grouping voice impairment scores, age =65 years, preoperative Voice Handicap Index 10 score = 3 and thyroidectomy past history were independent risk factors of voice impairment.

Objectives:Nasal septal deviation (NSD) is a common dilemma which cause nasal obstruction. Septoplasty is usually accomplished to solve nasal obstruction in patients with NSD. NSD is related strongly with hypoxia. Hypoxic conditions increase oxidative DNA damage in cells. This study aimed to investigate the effect of septoplasty on the level of antioxidant agents in patients with marked NSD. Methods: Sixty-one patients who submitted to septoplasty were involved in our prospective investigation. Results: The difference between the pre- and postoperative levels of MDA and 8-OHdG/106 dG was statistically significant. Conclusions: Septoplasty is an elective surgery performed to prevent the decrease in quality of life due to nasal obstruction and frequent respiratory tract infections in patients with NSD. As seen in this study, septoplasty is an urgent surgery that should be performed urgently to prevent DNA damage in patients with NSD

Liposarcoma is the most common form of soft-tissue sarcoma, only 3-8% have a head and neck location. They are commonly found in the retroperitoneum and on the limbs, laryngeal and hypopharyngeal presentation are extremely rare and less than 40 cases have been reported in literature. We present the case of a 50-year-old man with no prior history, who developed two contiguous hypopharyngeal liposarcomas.

Infectious mononucleosis is caused by Epstein-Barr virus, which infects more than 98% of the worlds adult population. Approximately 90% of adults become antibody-positive before the age of 30. The ages of 15-24 years are the most likely time for the onset of symptoms. We report the case of a 13-year-old girl who came to our emergency department for bilateral erythematous-poltaceous tonsillitis complicated by dysphagia and dyspnea. She had a diagnosis of infectious mononucleosis. For some hours the young woman presented an inconsistency between a marked respiratory distress and the patency of her upper airways. Finally the clinical picture fell suddenly, requiring an emergency tracheotomy to ensure a patent airway. In the following days a diagnosis of a left parapharyngeal abscess was reached. A tonsillectomy with drainage of the parapharyngeal abscess was required. It is well known that infectious mononucleosis is typically a silent infection. We describe the case of a girl who risked losing her life due to aggressive infectious mononucleosis, and how we treated her. Such a complicated case has never been described in Literature.

Sino-maxillary mucormycosis is an opportunistic, aggressive, invasive and fulminant fungal infection, which has the ability to rapidly cross anatomical barriers, causing extensive hard and soft tissue destruction, leading to significant cosmetic deformity, functional debility and morbidity. It usually affects susceptible, debilitated or immunocompromised individuals. A comprehensive Review Paper is presented, with a descriptive report on an unusual Case presentation, involving the dentoalveolar complex which thereafter invaded the maxillary antrum, in an otherwise healthy, adult patient with nil comorbidities. A probable intraoral portal of entry, and a likely iatrogenic etiopathogenesis resulting from inoculation of the fungus or its spores during dental extractions carried out in an unsterile setting, has been considered and elucidated. An emphasis has been placed on according a high index of suspicion in diagnosis of this fungal infection even in immunocompetent and healthy adults, presenting with a seemingly simple, deceptively indolent odontogenic infection. The importance of careful, albeit rapid differential diagnosis, and a prompt and aggressive medical-surgical treatment protocol instituted immediately following a confirmatory diagnosis, helps in limiting the spread and degree of destruction which can be caused by this potentially lethal fungal infection.