Obesity is the most prevalent nutritional dysfunction in society and the vital risk determinant for several relevant disorders. The first step of obesity assessment is calculated anthropometric measures and, secondly, measure biological and nutritional profiles. The current purpose is to investigate the relationship between BMI with biochemical profile, Vitamin B12, Fe, and cortisol in the volunteer’s population. There is an appositively connection between body mass index (BMI) with cortisol, liver and kidney profile, fasting blood sugar (FBS), Cholesterol, triglyceride, and low-density lipoprotein (LDL) and negative relationship between BMI and Vitamin B12, Fe, and high-density lipoprotein (HDL) in the present study. There is a significant elevation of cortisol, lipid profile, FBS, liver, and kidney function with BMI in the current work in females more than males compared to a reference range, and a significant decrease in Fe and vitamin B that can be due to diet habits, BMI, malabsorption in obesity condition, hormones affect or genetic variations between male and female. That will need further investigation.

ackground: The aim of this study was to investigate the antimicrobial activity of Mentha piperita , Withania somnifera and Rosmarinus officinalis extract on antibiotic resistant Escherichia coli isolated from poultry stool in Zabol city. Materials & Methods: The extract of Mentha piperita, Rosmarinus officinalis and Withania somnifera was prepared by rotary machine. Escherichia coli strains were isolated from poultry stool samples. Minimum inhibitory concentration and minimum bactericidal concentration were determined by microdilution method. Results: The results of this study showed that Mentha piperita extract showed the highest inhibitory ratio compared to other extracts. The minimum inhibitory concentration was 3.1 ppm, with 5 strains inhibited at this concentration. Discussion: The results of this study could be an effective strategy for production and preparation of medicinal plants to help treating E. coli infections.

The metabolic disorders are main and increasing public-health and clinical challenge worldwide because of urbanization, excessive energy intake, increasing obesity, and sedentary life styles. According to International Diabetes Federation (IFD) diabetes is one of the major metabolic disorders and a dangerous risk factor for heart problems. Twenty five percent of the world’s adults have metabolic disorders. Recently in year 2013 the American Heart Association also reported that adults have abnormal serum lipid profile. Allopathic drugs used as hypolipidemic agents have number of unwanted effects. Herbal therapy for Hyperlipidemia is getting attention due to their less frequent side effects. In this study we have compared hypolipidemic effects of Fenofibrate 40 mg with Nigella sativa. Seventy five hyperlipidemic patients from National Hospital Lahore were enrolled for study. Consent was taken from all enrolled participants and were divided in three equal numbers ie; twenty five in each group. Group 1 was on Nigella sativa, group 2 was on Gemfibrozil and third group was on placebo therapy. They were advised to take drugs for two months. After completion of study pretreatment and post treatment values of LDL cholesterol were analyzed statistically. In 25 patients who were on Nigella sativa, their LDL cholesterol decreased from 191.14±3.45 to 159.40±2.98 mg/dl. 31.7 mg/dl LDL reduction was observed when compared with placebo group. In 25 patients who were on Fenofibrate 40 mg, their LDL cholesterol decreased from 197.77±3.91 mg/dl to 159.62±2.20 mg/dl. LDL reduction in this group was 38.2 mg/dl. These changes are highly significant with p-values of <0.001. We concluded from this study that hypolipidemic characteristic of Nigella sativa is comparable and therapeutically as effective as traditionally used hypolipidemic medication Fenofibrate.