Digital necrosis is a clinical manifestation of a general or locoregional pathology and represents the ultimate stage of distal ischemia (1). It is more likely to be the consequence of a macroangiopathy which can also sometimes be associated with a microangiopathy. The necrosis of fingers and toes may be caused by a great variety of diseases including collagen vascular diseases (systemic scleroderma…), arteriopathies, vasculitis, haemopathies, occupational diseases and many others (2).

Giardiasis is a widespread invasion by protozoa, mainly affecting children, especially young children. We have studied patients with latent, subclinical and clinical forms of giardiasis. Timely diagnosis and targeted treatment can prevent severe forms of giardiasis. We have divided the latent, subclinical and clinical forms of giardiasis. In subclinical and clinical forms of giardiasis, pain in the abdomen, a syndrome of intestinal and gastric dyspepsia were observed. With giardiasis, children are prescribed dietary and drug therapy

Women in India are regarded as one of the countrys most valuable resources. Working women of India are characterized by growth and development, but they are vulnerable often by several factors which affect their health and safety. The health problems of women working on Nightshift is one of the major areas that need urgent attention from public health

Background: Road traffic accident (RTA) is one of the commonest causes of death among the healthy population and it’s among the leading cause of death due to human errors. Globally, it has contributed significantly to reducing the workforce as well as increasing the family expenditure on preventable health conditions. It is grossly underreported with no clear data on annual death reports, especially in most developing countries. Objectives: To determine the rate of death from a head injury due to road traffic accidents, risk factors; the commonly injured anatomical regions and immediate cause of death from autopsy examination of victims. Methods: This was a prospective longitudinal study in which 86 victims with CORONER FORM D were sampled recruited for the study. Primary data were obtained using the Crash Report Form (CRF) from the Federal Road Safety Corps, oral interviews from deceased relatives and security personnel who brought the victims, and subsequently, Coroner form D was used to obtain /record the findings of autopsy examination. Data was analysed using Statistical Product and Service Solutions (SPSS) version 25.0 (Armonk, NY). Results: The rate of death from a head injury due to RTA in Port Harcourt was 48.84%. The mean age of victims examined at autopsy was 28.61 ± 9.22 with a modal age group of 20-29. Majority of the victims were males [52(65.82%)], passengers [36(42%)], had superficial autopsy [32(37.20%)], multiple injuries [40 (46.51%)]. The commonest cause of immediate fatality was head injury (48.8%) followed by haemorrhage and shock 31(36.1%). Over speeding was the most common human risk factor (50%), followed by sleep/fatigue (10%). The commonest mechanical and environmental risk factors identified were brake failure and burst tyres (8%), and potholes (6%) respectively. Conclusion: The commonest cause of death among victims of RTA in Port Harcourt, Rivers State, Nigeria is head injury. Over speeding, sleep/fatigue, brake failure and burst tyres and pot holes are the risk factors for RTA in Port Harcourt. Measures targeted at controlling these risk factors would help reduce morbidity and mortalities associated with RTA

Splenic hamartoma is a rare, benign vascular proliferation that is often found incidentally while working up for other complaints or at autopsy. Women more commonly present with symptoms related to mass effect than man. Although rendering a diagnosis can be difficult, endothelial cells that are positive for CD8 are a key feature that differentiate hamartoma from other vascular lesions of the spleen. Clinical, radiologic, and histologic correlation is essential to ensure this benign lesion is not mistaken for malignancy. In our case, a teenage was diagnosed with splenic hamartoma.

Behcets disease (BD) is a rare condition, considered as a variable vessel vasculitis with multi-system involvement, characterized by the triad of recurrent mouth and genital ulcers with eye involvement, also may involve joints, skin, central nervous system, and gastrointestinal tract with important heterogeneity among patients regarding demographic features and organ manifestations. BD has a worldwide distribution. However, it is observed commonly among populations living along the historic Silk Road.The etiology of the disease remains unknown, but the most widely held hypothesis of disease pathogenesis is that of a profound inflammatory response triggered by an infectious agent in a genetically susceptible host. Number of reported cases is inexplicably low in sub-Saharan region and especially lowest in West Africa where only few cases have been reported. The aim of this presentation is to announce the first case description of BD in Gambia as well as, to sensitize physicians, Internal Medicine residents and general practitioners in our sub region with the pattern of the disease, as only way to reduce the diagnosis time frame

Introduction: Pulmonary tuberculosis has been of great interest for us given the high number of cases in our community at the Mexican-American border, however, this abundance of patients allows us to observe whether there is an association between the previously described development of hyponatremia and mortality in these patients. Objective: To determine the association between mortality and hyponatremia in patients with pulmonary tuberculosis. Material and Methods: We analyzed the electronic health record of patients with a pulmonary tuberculosis diagnosis from a 4-year period in the General Hospital of Mexicali, in México. Inclusion criteria were patients over the age of 18, a pulmonary tuberculosis diagnosis, and complete laboratory tests. The collected data was then analyzed through descriptive statistics. Results: 116 patients with pulmonary tuberculosis were included, of which 91 (78.4%) were male. A history of past Infection with the Human immunodeficiency virus and previous tuberculosis infection were shown to correlate with higher mortality and requirement of intensive care. The logistic regression analysis showed that hyponatremia had no association with mortality or the need for intensive care. Complications such as Acute respiratory distress syndrome and Acute kidney injury were related to higher mortality and need for critical care. Conclusions: The incidence of hyponatremia was higher than previously described, but there was no statistical association between hyponatremia and mortality in comparison to patients with normal sodium. Among this study’s weaknesses, most patients were hospitalized at the time of diagnosis, implying they could already have had a complication, thus increasing the incidence.

Aims: To know the Psychological impact of Covid-19 Pandemic on Hospital staff. Methods: The survey was conducted during the first wave of COVID-19 between 4thJune 2020 to 5th July 2020 at St. Helens & Knowsley Teaching Hospitals NHS Trust. Permission was obtained from the Audit & Information Governance Department of St. Helens & Knowsley Teaching Hospitals NHS Trust. Survey was done through Survey Monkey web site and used staff hospital e mail addressess to communicate with the hospital staff. Results: COVID-19 Pandemic has significant effects on the mental health and wellbeing of Front Line Health Workers in UK as shown in this study. Our study showed that major depressive symptoms were more common in non-doctors and doctors were more non-depressed. [Figure 3] There was a slightly higher sub-threshold depression among doctors over other staff members. Altogether among both groups of the front the line health workers 57.79% were non-depressed, 25.32% had sub-threshold depressive symptoms, and 16.88% had major depressive symptoms. [Figure 3] Conclusions: It is noted from our study that Front Line Health Workers do not give priority to their mental health wellbeing, hence there should be a system to regularly assess mental health of Front Line Health Workers and they should be encouraged to seek advice which appeared lacking in the respondents. It is important to mention that during the first wave, behavior, pathology and treatment of COVID-19 was not understood, and NHS staff at St. Helens & Knowsley Teaching Hospitals NHS Trust, like many other health care workers risked their own lives as Front Line Health Workers. It is not surprising that there was an impact on psychological wellbeing in such challenging circumstances.

Background Coronavirus disease 2019 (COVID-19) has been a major threat to health around the world as it causes significant morbidity and mortality. SARS-CoV-2 infection induces severe inflammation in lungs and multi-organs therefore, the Janus kinase (JAK) inhibitor known as baricitinib was proposed as a treatment for COVID-19 because of its anti-inflammatory and potential antiviral effects. It may improve survival in patients with severe Covid-19 infection. The efficacy and safety of Baricitinib therapy in severe COVID-19 infection in Myanmar was not known clearly.

In recent years, there has been an increase in the incidence of duodenal ulcer and an increase in the number of complicated forms. Bleeding from duodenal ulcers is the most formidable complication and occupies one of the first places in the structure of mortality from duodenal ulcer. The anamnestic, clinical features and pH values ??in children with duodenal ulcer were studied. The study allows us to consider sex, age, heredity, erosive nature of gastroduodenitis, multiple ulcers, high bacterial contamination, low pH in the antroduodenal zone as factors for the complicated course of duodenal ulcer