Objective: Coronary artery ectasia (CAE) is a cardiovascular disease characterized by dilatation of the coronary arteries and microvascular coronary ischemia. P-wave peak time duration (PWPT), T wave peak to end (Tp-Te) interval and Tp-Te/QS ratio are electrocardiographic (ECG) repolarization parameters associated with an increased risk of arrhythmia. Although awareness of CAE has increased in recent years, there is a paucity of available data on its arrhythmogenic effects. This study aims to evaluate the relationship between CAE and repolarization parameters as PWPT, Tp-Te interval and Tp-Te/QS ratio. Material and Methods: Retrospective data analysis of 45 patients with CAE and 51 control patients with normal coronary anatomy was performed. Clinical data, electrocardiogram results and coronary angiography results were analyzed. Among ECG parameters, PWPT, Tp-Te interval and Tp-Te/QTc ratios were particularly emphasized. Results: In the comparison between the CAE group and the control group, Tp-Te and Tp-Te/QTc ratios were significantly higher in CAE patients (p=0.013 and p=0.008, respectively). However, no significant difference was found in the PWPT range (p=0.289). Conclusion: This study reveals the existence of an association with ECG parameters reflecting myocardial repolarization in CAE patients. Especially increased Tp-Te and Tp-Te/QTc ratios indicate that the risk of ventricular arrhythmogenicity may be increased in CAE patients. The results emphasize the clinical importance of electrocardiogram investigations in patients with CAE.

Objective: Contrast-induced nephropathy (CIN) is still a complication that causes serious morbidity and mortality in patients with acute coronary syndrome. Early identification of high-risk patients is of great importance in terms of prognosis. In our research, we intended to inquire the predicative value of Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) rating in the development of CIN in non-ST-segment elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Material and Methods: Patients hospitalized in the coronary intensive care unit with the diagnosis of NSTEMI and who underwent PCI were retrospectively included. The patients were divided into two groups according to the development of CIN, and the two groups were statistically compared according to clinical, demographic and laboratory findings. ATRIA and CHA2DS2-VASc scores of the patients were calculated. Results: In our research, an overall of 550 patients who underwent PCI for NSTEMI were involved. After PCI, CIN was seen in 78 (14.1%) patients. Diabetes, heart failure, and previous strokes were higher in the group with CIN. The ejection fraction was significantly lower in the group with CIN (p<0.0001). CHA2DS2-VASc and ATRIA scores were significantly higher in patients who developed CIN compared to those who did not (p<0.0001). Conclusion: We showed that a high ATRIA score has predictive value in the development of CIN in NSTEMI patients undergoing PCI. The high CHA2DS2-VASc score, which has been shown to be associated with the development of CIN in patients with acute coronary syndrome in previous studies, may provide additional information to estimate the incidence of CIN development in our study.

Objective: Ischemic heart disease is the most common cause of sudden cardiac arrest (CA), which remains a serious public health problem worldwide. Guidelines include recommendations for the timing of coronary angiography (CAG) in successfully resuscitated CA patients based on electrocardiogram (ECG), pre-arrest complaint and clinical risk for ischemia. The aim of this study was to retrospectively analyze CA patients who were successfully resuscitated and underwent CAG. Material and Methods: The study included patients who were successfully resuscitated and underwent CAG between 01.01.2019-01.01.2022. In-hospital (IHCA) and out-of-hospital CA (OHCA) status, cardiopulmonary resuscitation (CPR) duration, ECGs after CPR, diagnoses, angiographic findings, infarct-related artery in case of occlusion, and mortality rates were evaluated. Results: The study included 130 patients. The mortality rate was 66.2%. There was no significant difference in mortality between IHCA and OHCA (p=0.327). Mortality was higher in non-ST-elevation myocardial infarction patients (p=0.020). It was found that CPR duration of =12.5 minutes could be used to predict mortality. Conclusions: In ST-segment elevation myocardial infarction patients presenting with CA, early and successful intervention had favorable effects on mortality. Patients with a CPR duration of less than 12.5 minutes had a higher chance of survival.

Objective: It’s known that prolonged high blood glucose levels during the course of diabetes mellitus (DM) lead to the development of autonomic neuropathy. In this study, we investigated the relationship between heart rate variability (HRV) and blood glycemic levels in patients clinically diagnosed with diabetes, in patients without any glucometabolic disorder, and in prediabetic patients. Material and Methods: In this study, 100 patients followed in Cardiology and General Internal Medicine outpatient clinics were evaluated retrospectively. Our study includes 3 different groups: 34 patients without any glucometabolic disorders, 35 patients followed up for prediabetes, and 31 patients diagnosed with diabetes. For the analysis of HRV parameters, standard deviation of normal RR intervals in 24 h (SDNN), SDNN index, root mean square of successive RR interval differences (rMSSD) and percetange of adjacent NN intervals differing by more than 50 milliseconds (pNN50), high frequency (HF), low frequency (LF) and LF/HF parameters were used. Results: As a result of post-hoc analyses for HRV parameters, SDNN, SDNN-index and rMSSD values were significantly lower in the diabetes group compared to the control group; very low frequency (VLF) value was found to be lower in the diabetes group compared to the other two groups. No-statistical difference was found between the groups for pNN50, HF, LF and LF/HF, but in the diabetes and pre-diabetes groups, pNN50, HF and LF were numerically lower than in the control group. Looking at the correlation between HRV parameters and FBS by group, a weak negative correlation was found between all variables except LF/HF. A weak to moderate negative correlation with HbA1c was found for SDNN, SDNN-index, rMSSD and VLF. When comparing HRV parameters by treatment type in diabetic patients, no statistically significant difference was found between patients using oral antidiabetic and those using insulin. When HRV parameters were compared by treatment status in the prediabetes group, there was no statistically significant difference between those receiving treatment and those not receiving treatment. Conclusions: We think that HRV parameters may be guiding in the diagnosis of cardiac-autonomic-neuropathy in patients with DM and blood glucose levels that have not yet reached pathological levels.